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Articles Published Processes
11/10/2014 7:09:00 PM | Browse: 1631 | Download: 1297
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Received |
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2013-10-29 15:38 |
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Peer-Review Started |
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2013-10-30 20:30 |
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To Make the First Decision |
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2013-12-16 17:32 |
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Return for Revision |
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2014-04-02 08:58 |
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Revised |
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2014-04-07 20:27 |
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Second Decision |
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2014-05-05 09:29 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-05-05 09:58 |
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Articles in Press |
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2014-05-23 10:09 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-10-25 13:59 |
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Publish the Manuscript Online |
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2014-11-10 19:10 |
Category |
Oncology |
Manuscript Type |
Topic Highlights |
Article Title |
S-1 in the treatment of pancreatic cancer
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Manuscript Source |
Invited Manuscript |
All Author List |
Kentaro Sudo, Kazuyoshi Nakamura and Taketo Yamaguchi |
Funding Agency and Grant Number |
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Corresponding Author |
Kentaro Sudo, MD, PhD, Department of Gastroenterology, Chiba Cancer Center, 666-2 Nitona-cho, Chuo-ku, Chiba 260-8717, Japan. kentarosudo9@yahoo.co.jp |
Key Words |
Pancreatic cancer; S-1; Chemotherapy; Randomized controlled trial; Chemoradiotherapy; Adjuvant therapy |
Core Tip |
This review article focuses on clinical trials of S-1-based chemotherapy for advanced pancreatic cancer. Recently, S-1 has been demonstrated to be non-inferior to gemcitabine in overall survival for metastatic or locally advanced pancreatic cancer in a large-scale phase Ⅲ study (GEST study). Furthermore, S-1 has been shown to be superior to adjuvant chemotherapy with gemcitabine in overall survival in patients with resected pancreatic cancer in another phase Ⅲ study (JASPAC-01 study). In addition to gemcitabine, S-1 is now considered one of the key drugs in Japan. |
Publish Date |
2014-11-10 19:10 |
Citation |
Sudo K, Nakamura K, Yamaguchi T. S-1 in the treatment of pancreatic cancer. World J Gastroenterol 2014; 20(41): 15110-15118 |
URL |
http://www.wjgnet.com/1007-9327/full/v20/i41/15110.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v20.i41.15110 |
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