Publication Name	World Journal of Gastroenterology
Manuscript ID	6864
Country	India

Received	2013-10-29 16:29
Peer-Review Started	2013-10-30 19:39
To Make the First Decision	2013-11-21 18:57
Return for Revision	2013-11-22 10:39
Revised	2013-12-31 03:59
Second Decision	2014-01-20 18:55
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-01-20 19:28
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-03-10 21:48
Typeset the Manuscript	2014-04-25 19:05
Publish the Manuscript Online	2014-05-18 12:31

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Antitubercular therapy in patients with cirrhosis: Challenges and options
Manuscript Source	Invited Manuscript
All Author List	Naveen Kumar, Chandan Kumar Kedarisetty, Sachin Kumar, Vikas Khillan and Shiv Kumar Sarin
Funding Agency and Grant Number
Corresponding Author	Dr. Shiv Kumar Sarin, MD, DM, DSc, FNA, Professor and Head, Department of Hepatology, Institute of Liver and Biliary Sciences, Vasant Kunj, Plot No.D-1, New Delhi 110070, India. shivsarin@gmail.com
Key Words	Antitubercular therapy; Drug hepatotoxicity; Multidrug-resistant tuberculosis; Immune dysfunction
Core Tip	Treatment of tuberculosis (TB) in patients with underlying cirrhosis is a challenge because of the compromised liver functions and high risk of hepatotoxicity. There is no consensus regarding the treatment and monitoring of TB in this group of patients. This paper reviews the differences in diagnosis, treatment, monitoring, hepatotoxicity and other issues in treatment of TB in patients with cirrhosis. Suggestions for treatment of TB in patients with different grades of cirrhosis, as well as monitoring guidelines, are provided. Finally, issues such as liver transplantation, multidrug-resistant TB and reactivation of TB by interferon are briefly reviewed.
Publish Date	2014-05-18 12:31
Citation	Kumar N, Kedarisetty CK, Kumar S, Khillan V, Sarin SK. Anti-tubercular therapy in patients with cirrhosis: Challenges and options. World J Gastroenterol 2014; 20(19): 5760-5772
URL	http://www.wjgnet.com/1007-9327/full/v20/i19/5760.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i19.5760

Full Article (PDF)	WJG-20-5760.pdf
Full Article (Word)	WJG-20-5760.doc
Manuscript File	6864-Review.docx
Answering Reviewers	6864-Answering reviews.pdf
Copyright License Agreement	6864-Copyright assignment.pdf
Peer-review Report	6864-Peer review(s).pdf
Scientific Editor Work List	6864-Scientific editor work list.doc