Publication Name	World Journal of Gastroenterology
Manuscript ID	6865
Country	Italy

Received	2013-10-29 16:41
Peer-Review Started	2013-10-30 19:32
First Decision by Editorial Office Director
Return for Revision	2014-02-17 22:14
Revised	2014-03-06 00:25
Publication Fee Transferred
Second Decision by Editor	2014-04-16 11:29
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2014-04-16 12:05
Articles in Press	2014-05-23 10:04
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-09-10 16:41
Publish the Manuscript Online	2014-10-01 20:25

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Surgery
Manuscript Type	Topic Highlights
Article Title	Problems faced by evidence-based medicine in evaluating lymphadenectomy for gastric cancer
Manuscript Source	Invited Manuscript
All Author List	Giuseppe Verlato, Simone Giacopuzzi, Maria Bencivenga, Paolo Morgagni and Giovanni De Manzoni
Funding Agency and Grant Number
Corresponding Author	Giovanni De Manzoni, MD, Unit of Upper GI Surgery, University of Verona, OCM Borgo Trento, Piazzale Stefani 1, 37126 Verona, Italy. giovanni.demanzoni@univr.it
Key Words	Gastric cancer; Surgical quality; Lymphadenectomy; Evidence-based medicine; National guidelines; Eastern Asia; United States
Core Tip	The extension of lymphadenectomy in advanced gastric cancer has been debated for several decades. Till recently Western surgeons supported limited lymphadenectomy in agreement with a Cochrane review and several meta-analyses, while Japanese surgeons preferred the extended procedure. Nowadays extended lymphadenectomy is considered the procedure of choice by most national guidelines. In gastric cancer surgery evidence-based medicine (EBM) is lagging behind national guidelines, rather than preceding and orienting them. To eliminate this lag, EBM should value to a larger extent Eastern Asian literature and should evaluate not only the quality of the study design but also the quality of surgical procedures.
Publish Date	2014-10-01 20:25
Citation	Verlato G, Giacopuzzi S, Bencivenga M, Morgagni P, De Manzoni G. Problems faced by evidence-based medicine in evaluating lymphadenectomy for gastric cancer. World J Gastroenterol 2014; 20(36): 12883-12891
URL	http://www.wjgnet.com/1007-9327/full/v20/i36/12883.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i36.12883

Full Article (PDF)	WJG-20-12883.pdf
Full Article (Word)	WJG-20-12883.doc
Manuscript File	6865-Review.doc
Answering Reviewers	6865-Answering reviewers.pdf
Copyright License Agreement	6865-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	6865-Language certificate.pdf
Peer-review Report	6865-Peer review(s).pdf
Scientific Editor Work List	6865-Scientific editor work list.doc