Publication Name	World Journal of Psychiatry
Manuscript ID	68685
Country	Mexico

Received	2021-05-31 06:59
Peer-Review Started	2021-05-31 07:02
To Make the First Decision
Return for Revision	2021-07-14 16:38
Revised	2021-08-10 10:46
Second Decision	2022-01-15 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-01-17 05:33
Articles in Press	2022-01-17 05:33
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-02-09 08:10
Publish the Manuscript Online	2022-02-17 08:22

ISSN	2220-3206 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Neurosciences
Manuscript Type	Review
Article Title	Insights into myelin dysfunction in schizophrenia and bipolar disorder
Manuscript Source	Invited Manuscript
All Author List	Marcela Valdés-Tovar, Alejandra Monserrat Rodríguez-Ramírez, Leslye Rodríguez-Cárdenas, Carlo E Sotelo-Ramírez, Beatriz Camarena, Marco Antonio Sanabrais-Jiménez, Héctor Solís-Chagoyán, Jesús Argueta and Germán Octavio López-Riquelme
ORCID	Author(s) ORCID Number Marcela Valdés-Tovar http://orcid.org/0000-0002-5540-7321 Alejandra Monserrat Rodríguez-Ramírez http://orcid.org/0000-0002-9248-0472 Leslye Rodríguez-Cárdenas http://orcid.org/0000-0003-2456-3353 Carlo E Sotelo-Ramírez http://orcid.org/0000-0001-9924-1434 Beatriz Camarena http://orcid.org/0000-0001-7737-501X Marco Antonio Sanabrais-Jiménez http://orcid.org/0000-0002-7722-5940 Héctor Solís-Chagoyán http://orcid.org/0000-0003-0692-6931 Jesús Argueta http://orcid.org/0000-0003-3668-1066 Germán Octavio López-Riquelme http://orcid.org/0000-0002-8031-4522
Funding Agency and Grant Number	Funding Agency Grant Number Fondo Sectorial de Investigación para la Educación (FSIE SEP/CONACyT) to MV-T 287115 Fondo Sectorial de Investigación en Salud y Seguridad Social (FOSISS SS/IMSS/ISSSTE-CONACyT) to BC 261459
Corresponding Author	Marcela Valdés-Tovar, PhD, Research Scientist, Departamento de Farmacogenética, Subdirección de Investigaciones Clínicas, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Calzada México-Xochimilco No. 101, Col. San Lorenzo-Huipulco, Tlalpan, Mexico City 14370, Mexico. mvaldes@imp.edu.mx
Key Words	Myelin sheath; Oligodendroglia; Schizophrenia; Bipolar disorder; White matter
Core Tip	Schizophrenia and bipolar disorder are multifactorial neuropsychiatric entities that share clinical manifestations as well as alterations to brain structure and function, genetic characteristics, and neurobiological pathways. Among the main pathophysiological mechanisms shared by these conditions is oligodendroglial dysfunction. Scientific evidence that ranges from the microscale cellular and subcellular levels to the macroscale connectomic level strongly supports overall myelin dysfunction and brain disconnection as hallmarks of schizophrenia and bipolar disorder.
Publish Date	2022-02-17 08:22
Citation	Valdés-Tovar M, Rodríguez-Ramírez AM, Rodríguez-Cárdenas L, Sotelo-Ramírez CE, Camarena B, Sanabrais-Jiménez MA, Solís-Chagoyán H, Argueta J, López-Riquelme GO. Insights into myelin dysfunction in schizophrenia and bipolar disorder. World J Psychiatry 2022; 12(2): 264-285
URL	https://www.wjgnet.com/2220-3206/full/v12/i2/264.htm
DOI	https://dx.doi.org/10.5498/wjp.v12.i2.264

Full Article (PDF)	WJP-12-264.pdf
Full Article (Word)	WJP-12-264.docx
Manuscript File	68685_Auto_Edited.docx
Answering Reviewers	68685-Answering reviewers.pdf
Audio Core Tip	68685-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	68685-Conflict-of-interest statement.pdf
Copyright License Agreement	68685-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	68685-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	68685-Language certificate.pdf
Peer-review Report	68685-Peer-review(s).pdf
Scientific Misconduct Check	68685-Bing-Fan JR-2.png
Scientific Editor Work List	68685-Scientific editor work list.pdf
CrossCheck Report	68685-CrossCheck report.pdf
CrossCheck Report	68685-CrossCheck.png