Publication Name	World Journal of Gastroenterology
Manuscript ID	6876
Country	Italy

Received	2013-10-29 18:01
Peer-Review Started	2013-10-30 14:51
To Make the First Decision	2013-12-03 18:47
Return for Revision	2013-12-05 15:54
Revised	2013-12-25 23:23
Second Decision	2014-01-05 15:02
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-01-05 15:15
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-03-04 11:18
Publish the Manuscript Online	2014-03-18 14:14

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Medicine, General & Internal
Manuscript Type	Autobiography
Article Title	Hepatitis C virus and metabolic disorder interactions towards liver damage and atherosclerosis
Manuscript Source	Invited Manuscript
All Author List	Umberto Vespasiani-Gentilucci, Paolo Gallo, Antonio De Vincentis, Giovanni Galati and Antonio Picardi
Funding Agency and Grant Number
Corresponding Author	Antonio Picardi, MD, PhD, Internal Medicine and Hepatology Unit, University Campus Bio-Medico of Rome, Via Alvaro del Portillo 200, 00128 Rome, Italy. a.picardi@unicampus.it
Key Words	Hepatitis C virus; Metabolism; Insulin resistance; Diabetes mellitus; Steatosis; Fibrosis; Atherosclerosis; Cardiovascular risk
Core Tip	In this review we will analyze the mechanisms possibly contributing to the relationship between hepatitis C virus (HCV) infection and altered metabolism, as well as the clinical data suggesting that HCV-induced metabolic disorders favour both the progression of liver damage in terms of steatosis/fibrosis and the development of atherosclerosis. Particular attention will be devoted to the highly debated topic concerning the link between HCV infection and cardiovascular disease, a time-related interpretation on the factors impacting cardiovascular risk in the course of HCV infection will be provided, and, finally, the complex virus/host interplay will be graphically synthesized to provide an intuitive picture of the item.
Publish Date	2014-03-18 14:14
Citation	Vespasiani-Gentilucci U, Gallo P, De Vincentis A, Galati G, Picardi A. Hepatitis C virus and metabolic disorder interactions towards liver damage and atherosclerosis. World J Gastroenterol 2014; 20(11): 2825-2838
URL	http://www.wjgnet.com/1007-9327/full/v20/i11/2825.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i11.2825

Full Article (PDF)	WJG-20-2825.pdf
Full Article (Word)	WJG-20-2825.doc
Manuscript File	6876-Review.doc
Answering Reviewers	6876-Answering reviewers.pdf
Copyright License Agreement	6876-Copyright assignment.pdf
Peer-review Report	6876-Peer review(s).pdf
Scientific Editor Work List	6876-Scientific editor work list.doc