Publication Name	World Journal of Stem Cells
Manuscript ID	6878
Country	Brazil

Received	2013-10-29 18:16
Peer-Review Started	2013-10-30 16:20
To Make the First Decision	2013-11-19 13:00
Return for Revision	2013-11-20 09:04
Revised	2013-12-14 01:29
Second Decision	2014-03-12 18:35
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-03-12 18:42
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-04-02 14:30
Typeset the Manuscript	2014-04-19 17:32
Publish the Manuscript Online	2014-04-28 14:14

ISSN	1948-0210 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Neurosciences
Manuscript Type	Topic Highlights
Article Title	Neurotrauma and mesenchymal stem cells treatment: From experimental studies to clinical trials
Manuscript Source	Invited Manuscript
All Author List	Ana Maria Blanco Martinez, Camila de Oliveira Goulart, Bruna dos Santos Ramalho, Júlia Teixeira Oliveira and Fernanda Martins Almeida
Funding Agency and Grant Number
Corresponding Author	Ana Maria Blanco Martinez, MD, PhD, Laboratory of Neurodegeneration and Repair, Institute of Biomedical Sciences, Health Science Center, bloco F - sala 12, 21941-902, Rio de Janeiro, Brazil. martinez@histo.ufrj.br
Key Words	Neurotrauma; Stem cell therapy; Mesenchymal stem cells; Pre-clinical studies; Clinical trials
Core Tip	Basic and pre-clinical studies have highlighted the positive effects of mesenchymal stem cell (MSC) treatment after spinal cord injury (SCI) and nerve trauma. There are many pre-clinical studies on MSC treatment for SCI and nerve injuries. However, the same is not true for clinical trials, particularly those concerned with nerve trauma. As for clinical trials for SCI, the results obtained so far are not as beneficial as those described in experimental studies. For these reasons basic and pre-clinical studies dealing with MSC therapy should emphasize the standardization of protocols that could be translated to the clinical set with consistent and positive outcomes.
Publish Date	2014-04-28 14:14
Citation	Martinez AMB, Goulart CO, Ramalho BS, Oliveira JT, Almeida FM. Neurotrauma and mesenchymal stem cells treatment: From experimental studies to clinical trials. World J Stem Cells 2014; 6(2): 179-194
URL	http://www.wjgnet.com/1948-0210/full/v6/i2/179.htm
DOI	http://dx.doi.org/10.4252/wjsc.v6.i2.179

Full Article (PDF)	WJSC-6-179.pdf
Full Article (Word)	WJSC-6-179.doc
Manuscript File	6878-Review.doc
Answering Reviewers	6878-Answering reviewers.pdf
Copyright License Agreement	6878-Copyright assignment.pdf
Peer-review Report	6878-Peer review(s).pdf
Scientific Editor Work List	6878-Scientific editor work list.doc