Publication Name	World Journal of Gastroenterology
Manuscript ID	69033
Country	Hungary

Received	2021-06-16 10:46
Peer-Review Started	2021-06-16 10:50
To Make the First Decision
Return for Revision	2021-07-14 02:54
Revised	2021-07-25 20:28
Second Decision	2021-09-14 03:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2021-09-16 23:45
Articles in Press	2021-09-16 23:45
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-10-11 00:35
Publish the Manuscript Online	2021-10-27 07:14

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Meta-Analysis
Article Title	Prophylactic transcatheter arterial embolization reduces rebleeding in non-variceal upper gastrointestinal bleeding: A meta-analysis
Manuscript Source	Unsolicited Manuscript
All Author List	Eszter Boros, Zoltán Sipos, Péter Hegyi, Brigitta Teutsch, Levente Frim, Szilárd Váncsa, Szabolcs Kiss, Fanni Dembrovszky, Eduard Oštarijaš, Andrew Shawyer and Bálint Erőss
ORCID	Author(s) ORCID Number Eszter Boros http://orcid.org/0000-0002-7831-163X Zoltán Sipos http://orcid.org/0000-0001-7845-8116 Péter Hegyi http://orcid.org/0000-0003-0399-7259 Brigitta Teutsch http://orcid.org/0000-0002-9530-7886 Levente Frim http://orcid.org/0000-0003-0097-6663 Szilárd Váncsa http://orcid.org/0000-0002-9347-8163 Szabolcs Kiss http://orcid.org/0000-0001-5032-866X Fanni Dembrovszky http://orcid.org/0000-0001-6953-3591 Eduard Oštarijaš http://orcid.org/0000-0001-9999-9886 Andrew Shawyer http://orcid.org/0000-0003-1700-3307 Bálint Erőss http://orcid.org/0000-0003-3658-8427
Funding Agency and Grant Number	Funding Agency Grant Number Economic Development and Innovation Operative Programme Grant GINOP 2.3.2-15-2016-00048 Economic Development and Innovation Operative Programme Grant GINOP-2.3.4-15-2020-00010 Human Resources Development Operational Programme Grant EFOP-3.6.2-16-2017-00006 Human Resources Development Operational Programme Grant EFOP-3.6.1.-16-2016-00004
Corresponding Author	Bálint Erőss, MD, PhD, Assistant Professor, Doctor, Doctor, Institute for Translational Medicine, University of Pecs, Medical School, 12 Szigeti Street, Pécs 7624, Hungary. eross.balint@pte.hu
Key Words	Prophylactic transcatheter arterial embolization; Non-variceal upper gastrointestinal bleeding; Rebleeding; Reintervention; Meta-analysis; Review
Core Tip	Rebleeding remains a significant concern in patients with non-variceal upper gastrointestinal bleeding (NVUGIB), despite the improvements in endoscopic and pharmacologic treatments. Our systematic review and meta-analysis indicate that prophylactic transcatheter arterial embolization (PTAE) compared to standard of care is accompanied by lower odds of rebleeding, need for rescue surgery, and reinterventions NVUGIB. However, we could not justify a beneficial effect of PTAE on mortality rates compared with the standard of care. In line with our results, we suggest using PTAE in selected cases, where risk stratification predicts high rebleeding risk or the anatomical situation makes the secure and permanent endoscopic hemostasis impossible.
Publish Date	2021-10-27 07:14
Citation	Boros E, Sipos Z, Hegyi P, Teutsch B, Frim L, Váncsa S, Kiss S, Dembrovszky F, Oštarijaš E, Shawyer A, Erőss B. Prophylactic transcatheter arterial embolization reduces rebleeding in non-variceal upper gastrointestinal bleeding: A meta-analysis. World J Gastroenterol 2021; 27(40): 6985-6999
URL	https://www.wjgnet.com/1007-9327/full/v27/i40/6985.htm
DOI	https://dx.doi.org/10.3748/wjg.v27.i40.6985

Full Article (PDF)	WJG-27-6985.pdf
Full Article (Word)	WJG-27-6985.docx
PRISMA 2009 Checklist	69033-PRISMA-2009-Checklist-revision.pdf
Manuscript File	69033_Auto_Edited.docx
Answering Reviewers	69033-Answering reviewers.pdf
Audio Core Tip	69033-Audio core tip.mp3
Biostatistics Review Certificate	69033-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	69033-Conflict-of-interest statement.pdf
Copyright License Agreement	69033-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	69033-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	69033-Language certificate.pdf
Supplementary Material	69033-Supplementary material.pdf
Peer-review Report	69033-Peer-review(s).pdf
Scientific Editor Work List	69033-Scientific editor work list.pdf
CrossCheck Report	69033-CrossCheck report.pdf