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Articles Published Processes
8/28/2014 9:54:00 AM | Browse: 1090 | Download: 1162
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Received |
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2013-10-29 21:51 |
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Peer-Review Started |
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2013-10-31 12:10 |
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To Make the First Decision |
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2013-12-04 09:25 |
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Return for Revision |
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2013-12-05 18:22 |
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Revised |
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2014-01-09 23:28 |
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Second Decision |
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2014-01-20 17:16 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-01-20 18:19 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2014-02-25 16:34 |
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Typeset the Manuscript |
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2014-04-27 19:22 |
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Publish the Manuscript Online |
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2014-05-14 10:58 |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Topic Highlights |
Article Title |
Role of epithelial-mesenchymal transition in gastric cancer initiation and progression
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Manuscript Source |
Invited Manuscript |
All Author List |
Zhao Peng, Chen-Xiao Wang, Er-Hu Fang, Guo-Bin Wang and Qiang Tong |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Natural Science Foundation of China |
81172186 |
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Corresponding Author |
Qiang Tong, Professor, Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan 430022, Hubei Province, China. qiangtong@hust.edu.cn |
Key Words |
Epithelial-mesenchymal transition; Gastric cancer; Tumorigenesis; Tumor progression; Cancer stem cells |
Core Tip |
Gastric cancer is responsible for numerous deaths worldwide; therefore, investigations into its initiation and development are of great importance. Recent evidence has shown that epithelial-mesenchymal transition (EMT) plays an important role in tumorigenesis and progression. In this review, we investigate the role of EMT in gastric cancer. We discuss the role of EMT in both carcinogenesis and progression. We also summarize the regulators and signal pathways involved in EMT. A systemic understanding of the role of EMT could be helpful for the early detection and effective treatment of gastric cancer. |
Publish Date |
2014-05-14 10:58 |
Citation |
Peng Z, Wang CX, Fang EH, Wang GB, Tong Q. Role of epithelial-mesenchymal transition in gastric cancer initiation and progression. World J Gastroenterol 2014; 20(18): 5403-5410 |
URL |
http://www.wjgnet.com/1007-9327/full/v20/i18/5403.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v20.i18.5403 |
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