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2/10/2022 2:26:33 PM | Browse: 296 | Download: 574
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 69357
Country China
Received
2021-08-12 08:05
Peer-Review Started
2021-08-12 08:05
To Make the First Decision
Return for Revision
2021-11-08 07:33
Revised
2021-11-20 15:59
Second Decision
2022-01-17 05:42
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-01-20 05:14
Articles in Press
2022-01-20 05:14
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-01-25 16:50
Publish the Manuscript Online
2022-02-10 14:26
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Retrospective Study
Article Title Predictive value of serum alpha-fetoprotein for tumor regression after preoperative chemotherapy for rectal cancer
Manuscript Source Unsolicited Manuscript
All Author List Da-Kui Zhang, Jun Qiao, Shao-Xuan Chen, Zhi-Yong Hou and Jian-Zheng Jie
ORCID
Author(s) ORCID Number
Da-Kui Zhang http://orcid.org/0000-0001-7599-3404
Jun Qiao http://orcid.org/0000-0003-3840-0969
Shao-Xuan Chen http://orcid.org/0000-0003-4157-5030
Zhi-Yong Hou http://orcid.org/0000-0002-5633-8727
Jian-Zheng Jie http://orcid.org/0000-0003-1158-4972
Funding Agency and Grant Number
Funding Agency Grant Number
Youth Foundation of China–Japan Friendship Hospital 2019-1-QN-42
Corresponding Author Jian-Zheng Jie, MD, Doctor, Department of General Surgery, China-Japan Friendship Hospital, No. 2 Yinghuayuan East Street, Beijing 100029, China. dakuizhang2021@126.com
Key Words Rectal cancer; Preoperative chemotherapy; Alpha-fetoprotein; Predictive value; Tumor
Core Tip We analyzed 125 patients with locally advanced rectal cancer retrospectively. The patients received 6 cycles of preoperative chemotherapy (mFOLFOX6 every 2 wk). Serum α-fetoprotein (AFP) of 26 patients rose slightly and returned to normal in two months. These patients achieved better tumor regression grade (TRG0-1) than those with normal AFP (61.5% vs 39.4%). Patients with a slight increase of serum AFP showed better tumor regression during preoperative chemotherapy, and were more likely to achieve pathological complete response (30.8% vs 12.1%).
Publish Date 2022-02-10 14:26
Citation Zhang DK, Qiao J, Chen SX, Hou ZY, Jie JZ. Predictive value of serum alpha-fetoprotein for tumor regression after preoperative chemotherapy for rectal cancer. World J Gastrointest Oncol 2022; 14(2): 525-532
URL https://www.wjgnet.com/1948-5204/full/v14/i2/525.htm
DOI https://dx.doi.org/10.4251/wjgo.v14.i2.525
Full Article (PDF) WJGO-14-525.pdf
Full Article (Word) WJGO-14-525.docx
Manuscript File 69357_Auto_Edited.docx
Answering Reviewers 69357-Answering reviewers.pdf
Audio Core Tip 69357-Audio core tip.m4a
Biostatistics Review Certificate 69357-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 69357-Conflict-of-interest statement.pdf
Copyright License Agreement 69357-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 69357-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 69357-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 69357-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 69357-Language certificate.pdf
Peer-review Report 69357-Peer-review(s).pdf
Scientific Misconduct Check 69357-Bing-Fan JR-2.png
Scientific Editor Work List 69357-Scientific editor work list.pdf