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Articles Published Processes
12/16/2021 7:46:10 AM | Browse: 487 | Download: 914
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Received |
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2021-06-30 01:17 |
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Peer-Review Started |
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2021-06-30 01:22 |
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To Make the First Decision |
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Return for Revision |
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2021-07-28 05:01 |
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Revised |
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2021-09-01 02:27 |
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Second Decision |
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2021-12-01 03:22 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-12-02 01:48 |
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Articles in Press |
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2021-12-02 01:48 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-12-09 07:28 |
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Publish the Manuscript Online |
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2021-12-16 07:46 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pharmacology & Pharmacy |
| Manuscript Type |
Review |
| Article Title |
Thioredoxin interacting protein, a key molecular switch between oxidative stress and sterile inflammation in cellular response
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Islam N Mohamed, Luling Li, Saifudeen Ismael, Tauheed Ishrat and Azza B El-Remessy |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Azza B El-Remessy, PharmD, PhD, Pharmacist, Department of Pharmacy, Doctors Hospital of Augusta, -, Augusta, GA 30907, United States. aelremessy@outlook.com |
| Key Words |
Thioredoxin interacting protein; NOD-like receptor pyrin domain containing 3; Inflammasome; Interleukin 1b; Inflammation; Obesity; High-fat diet; Ischemia; Reperfusion; Oxidative stress |
| Core Tip |
Inflammation has been postulated as the central pathway involved in maintaining homeostasis and in cellular response to insults. High fat diet-induced inflammasome activation have been reported to predispose microvascular diseases including retinopathy, and nonalcoholic fatty liver disease. Inflammation can alter vascular recovery in response to ischemic insult including ischemic retinopathy, stroke and critical limb ischemia. Thioredoxin interacting protein (TXNIP) is required for the activation but not necessarily for expression of NOD-like receptor pyrin domain containing 3-inflammasome resulting in initiation or exacerbation of the disease state. A list of natural antioxidants or repurposed drugs is included to modulate TXNIP expression. |
| Publish Date |
2021-12-16 07:46 |
| Citation |
Mohamed IN, Li L, Ismael S, Ishrat T, El-Remessy AB. Thioredoxin interacting protein, a key molecular switch between oxidative stress and sterile inflammation in cellular response. World J Diabetes 2021; 12(12): 1979-1999 |
| URL |
https://www.wjgnet.com/1948-9358/full/v12/i12/1979.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v12.i12.1979 |
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