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Articles Published Processes
8/29/2014 11:57:00 AM | Browse: 1415 | Download: 1155
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Received |
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2013-10-30 19:43 |
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Peer-Review Started |
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2013-11-01 11:55 |
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To Make the First Decision |
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2013-12-16 18:12 |
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Return for Revision |
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2013-12-18 10:14 |
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Revised |
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2014-01-15 06:34 |
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Second Decision |
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2014-04-16 11:18 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-04-16 12:15 |
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Articles in Press |
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2014-05-23 10:01 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-08-09 20:47 |
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Publish the Manuscript Online |
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2014-08-29 11:57 |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Topic Highlights |
Article Title |
Pancreatic ductal adenocarcinoma: Risk factors, screening, and early detection
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Manuscript Source |
Invited Manuscript |
All Author List |
Andrew E Becker, Yasmin G Hernandez, Harold Frucht and Aimee L Lucas |
Funding Agency and Grant Number |
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Corresponding Author |
Correspondence to: Aimee L Lucas, MD, MS, Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, One Gustave L Levy Place, Box 1069, New York, NY 10029, United States. aimee.lucas@mssm.edu |
Key Words |
Pancreatic neoplasms; Pancreas cancer screening; Genetic predisposition to disease; Hereditary breast and ovarian cancer syndrome; Lynch syndrome; Peutz-Jeghers; BRCA; PALB2; p16; Pancreatitis |
Core Tip |
Risk factors for developing pancreatic cancer include multiple genetic syndromes as well as modifiable risk factors. These factors can raise the risk of developing pancreatic cancer up to 132-fold over the general population. Several large-volume centers have initiated screening protocols, and consensus-based guidelines for screening high-risk groups have recently been published. The focus of this review will be both the genetic and modifiable risk factors implicated in pancreatic cancer, as well as a review of screening strategies and their diagnostic yields. |
Publish Date |
2014-08-29 11:57 |
Citation |
Becker AE, Hernandez YG, Frucht H, Lucas AL. Pancreatic ductal adenocarcinoma: Risk factors, screening, and early detection. World J Gastroenterol 2014; 20(32): 11182-11198 |
URL |
http://www.wjgnet.com/1007-9327/full/v20/i32/11182.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v20.i32.11182 |
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