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Articles Published Processes
11/25/2021 7:42:46 AM | Browse: 431 | Download: 794
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Received |
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2021-07-04 17:01 |
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Peer-Review Started |
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2021-07-04 17:06 |
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To Make the First Decision |
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Return for Revision |
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2021-07-13 23:59 |
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Revised |
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2021-07-14 22:50 |
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Second Decision |
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2021-09-07 03:25 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2021-09-08 18:25 |
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Articles in Press |
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2021-09-08 18:25 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-11-13 16:08 |
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Typeset the Manuscript |
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2021-11-24 02:41 |
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Publish the Manuscript Online |
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2021-11-25 07:42 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Proton pump inhibitors and colorectal cancer: A systematic review
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Agastya Patel, Piotr Spychalski, Magdalena Antoszewska, Jaroslaw Regula and Jarek Kobiela |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Jarek Kobiela, MD, PhD, Assistant Professor, Department of General, Endocrine and Transplant Surgery, Medical University of Gdansk, Marii Skłodowskiej-Curie 3a, Gdansk 80-210, Poland. grasper@tlen.pl |
| Key Words |
Colorectal cancer; Proton pump inhibitor; Carcinogenesis; Cancer epidemiology; Capecitabine; Translational medicine |
| Core Tip |
Proton pump inhibitors (PPI) are a widely, often inappropriately, used class of drugs. Through various mechanism, they are suspected to increase risk of gastrointestinal cancers, including colorectal cancer (CRC). The aim of this review is to summarize entirely of existing literature on the effect of PPI on CRC. The review assess basic research studies to identify mechanisms at play in this relationship, observational studies to determine if a causal association exists between PPI use and CRC incidence, and clinical studies to examine if PPI use during chemotherapy influences treatment efficacy and oncological outcomes. |
| Publish Date |
2021-11-25 07:42 |
| Citation |
Patel A, Spychalski P, Antoszewska M, Regula J, Kobiela J. Proton pump inhibitors and colorectal cancer: A systematic review. World J Gastroenterol 2021; 27(44): 7716-7733 |
| URL |
https://www.wjgnet.com/1007-9327/full/v27/i44/7716.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v27.i44.7716 |
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