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8/25/2014 9:54:00 AM | Browse: 845 | Download: 915
Publication Name World Journal of Transplantation
Manuscript ID 6958
Country Spain
Received
2013-11-06 17:06
Peer-Review Started
2013-11-08 19:46
To Make the First Decision
2013-12-13 13:37
Return for Revision
2013-12-17 16:24
Revised
2014-01-29 05:08
Second Decision
2014-02-19 11:19
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-02-19 11:42
Articles in Press
2014-05-23 13:20
Publication Fee Transferred
Edit the Manuscript by Language Editor
2014-03-17 14:25
Typeset the Manuscript
2014-06-30 10:26
Publish the Manuscript Online
2014-07-20 20:07
ISSN 2220-3230 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Transplantation
Manuscript Type Autobiography
Article Title Everolimus immunosuppression reduces the serum expression of fibrosis markers in liver transplant recipients
Manuscript Source Invited Manuscript
All Author List Ainhoa Fernández-Yunquera, Cristina Ripoll, Rafael Bañares, Marta Puerto, Diego Rincón, Ismael Yepes, Vega Catalina and Magdalena Salcedo
Funding Agency and Grant Number
Funding Agency Grant Number
Novartis Pharma Schweiz AG
Corresponding Author Magdalena Salcedo, Chief Doctor, Department of Liver Transplantation, Hospital General Gregorio Mara?ón, C/ Doctor Esquerdo no 46, 28028 Madrid, Spain. magdalena.salcedo@salud.madrid.org
Key Words Everolimus; Rapamycin; Liver fibrosis; Mammalian target of rapamycin; Transplantation
Core Tip This study tries to approach the possible antifibrotic effect of everolimus, a mammalian target of a rapamycin inhibitor, in the clinical setting. Some studies in animal models suggest that it could also have an antifibrotic effect. The main conclusion of this study is that liver transplantation recipients with everolimus monotherapy had less serum expression of transforming growth factor-? and hyaluronic acid than matched patients with anti-calcineurins that play an important role in liver fibrosis. The study offers the rationale for much needed future randomized controlled trials that evaluate the modulation of post-transplant fibrosis.
Publish Date 2014-07-20 20:07
Citation Fernández-Yunquera A, Ripoll C, Bañares R, Puerto M, Rincón D, Yepes I, Catalina V, Salcedo M. Everolimus immunosuppression reduces the serum expression of fibrosis markers in liver transplant recipients. World J Transplant 2014; 4(2): 133-140
URL http://www.wjgnet.com/2220-3230/full/v4/i2/133.htm
DOI http://dx.doi.org/10.5500/wjt.v4.i2.133
Full Article (PDF) WJT-4-133.pdf
Full Article (Word) WJT-4-133.doc
Manuscript File 6958-Review.doc
Answering Reviewers 6958-Answering reviewers.pdf
Copyright License Agreement 6958-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 6958-Language certificate.pdf
Peer-review Report 6958-Peer reviewer(s).pdf
Scientific Editor Work List 6958-Scientific editor work list.doc