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4/22/2022 10:52:23 AM | Browse: 837 | Download: 2479
Publication Name World Journal of Hepatology
Manuscript ID 69584
Country Denmark
Received
2021-07-05 10:41
Peer-Review Started
2021-07-05 10:47
First Decision by Editorial Office Director
2021-11-11 08:36
Return for Revision
2021-11-11 08:36
Revised
2021-11-22 10:13
Publication Fee Transferred
Second Decision by Editor
2022-03-22 06:26
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2022-03-27 06:44
Articles in Press
2022-03-27 06:44
Edit the Manuscript by Language Editor
2022-03-18 12:52
Typeset the Manuscript
2022-03-31 07:53
Publish the Manuscript Online
2022-04-22 10:52
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Meta-Analysis
Article Title Effects and safety of natriuretic peptides as treatment of cirrhotic ascites: A systematic review and meta-analysis
Manuscript Source Unsolicited Manuscript
All Author List Rasmus Hvidbjerg Gantzel, Mikkel Breinholt Kjær, Peter Jepsen, Niels Kristian Aagaard, Hugh Watson, Lise Lotte Gluud and Henning Grønbæk
ORCID
Author(s) ORCID Number
Rasmus Hvidbjerg Gantzel http://orcid.org/0000-0002-4589-6539
Mikkel Breinholt Kjær http://orcid.org/0000-0002-6385-5108
Peter Jepsen http://orcid.org/0000-0002-6641-1430
Niels Kristian Aagaard http://orcid.org/0000-0002-1524-8952
Hugh Watson http://orcid.org/0000-0002-6931-3158
Lise Lotte Gluud http://orcid.org/0000-0002-9462-4468
Henning Grønbæk http://orcid.org/0000-0001-8998-7910
Funding Agency and Grant Number
Corresponding Author Henning Grønbæk, MD, PhD, Doctor, Doctor, Professor, Research Associate, Department of Hepatology and Gastroenterology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, Aarhus N 8200, Denmark. henngroe@rm.dk
Key Words Atrial natriuretic peptide; B-type natriuretic peptide; Urodilatin; Cirrhosis; Ascites; Refractory ascites
Core Tip Pharmacotherapies for cirrhotic ascites have remained largely unchanged for the past four decades. 5%-10% of cirrhosis patients with ascites become refractory to available treatments, and the majority of these patients require frequent large-volume paracenteses. This justifies a continued search for new and improved treatments for ascites. This is the first systematic review and meta-analysis to investigate the effects and safety of natriuretic peptides as treatment of cirrhotic ascites. We demonstrate a significant natriuretic effect of intravenously administered atrial natriuretic peptide and summarise the safety findings.
Publish Date 2022-04-22 10:52
Citation Gantzel RH, Kjær MB, Jepsen P, Aagaard NK, Watson H, Gluud LL, Grønbæk H. Effects and safety of natriuretic peptides as treatment of cirrhotic ascites: A systematic review and meta-analysis. World J Hepatol 2022; 14(4): 827-845
URL https://www.wjgnet.com/1948-5182/full/v14/i4/827.htm
DOI https://dx.doi.org/10.4254/wjh.v14.i4.827
Full Article (PDF) WJH-14-827.pdf
Full Article (Word) WJH-14-827.docx