Publication Name	World Journal of Gastroenterology
Manuscript ID	6962
Country	France

Received	2013-10-31 08:52
Peer-Review Started	2013-10-31 16:22
To Make the First Decision	2013-12-16 17:31
Return for Revision	2013-12-17 19:43
Revised	2014-02-08 03:23
Second Decision	2014-03-19 13:55
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-03-19 15:00
Articles in Press	2014-05-23 11:30
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-04-02 21:34
Typeset the Manuscript	2014-05-27 09:53
Publish the Manuscript Online	2014-06-16 16:19

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Gender-related differences in irritable bowel syndrome: Potential mechanisms of sex hormones
Manuscript Source	Invited Manuscript
All Author List	Mathieu Meleine and Julien Matricon
Funding Agency and Grant Number
Corresponding Author	Mathieu Meleine, PhD, Department of Inflammation, Nutrition and Gut-Brain Axis Dysfunction, Inserm Unit 1073, Faculté de Médecine et Pharmacie, Université de Rouen, 22 Boulevard Gambetta, Cedex 1, 76183 Rouen, France. mathieu.meleine@hotmail.fr
Key Words	Irritable bowel syndrome; Pathophysiology; Gender; Sex hormones; Gut; Sensori-motricity; Neurosensitization; Stress; Immune activation; Permeabilization
Core Tip	This review summarizes the current knowledge on the role of ovarian hormones in the pathophysiology of irritable bowel syndrome (IBS). A better understanding of gender differences in IBS may help unveil some key mechanisms contributing to IBS development. We present data on: (1) the modulatory role of ovarian hormones on IBS symptoms; (2) influence of ovarian hormones on risk factors associated with IBS; and (3) potential mechanisms of action, by which ovarian hormones can modulate and/or induce IBS symptoms.
Publish Date	2014-06-16 16:19
Citation	Meleine M, Matricon J. Gender-related differences in irritable bowel syndrome: Potential mechanisms of sex hormones. World J Gastroenterol 2014; 20(22): 6725-6743
URL	http://www.wjgnet.com/1007-9327/full/v20/i22/6725.htm
DOI	10.3748/wjg.v20.i22.6725

Full Article (PDF)	WJG-20-6725.pdf
Full Article (Word)	WJG-20-6725.doc
Manuscript File	6962-Review.doc
Answering Reviewers	6962-Answering reviewers.pdf
Copyright License Agreement	6962-Copyright assignment.pdf
Peer-review Report	6962-Peer review(s).pdf
Scientific Editor Work List	6962-Scientific editor work list.doc