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12/14/2021 11:58:13 PM | Browse: 314 | Download: 645
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 69684
Country/Territory China
Received
2021-07-13 16:53
Peer-Review Started
2021-07-13 16:57
To Make the First Decision
Return for Revision
2021-08-10 15:41
Revised
2021-08-18 18:32
Second Decision
2021-10-22 06:45
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-10-25 01:50
Articles in Press
2021-10-25 01:50
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-10-06 11:15
Typeset the Manuscript
2021-12-07 04:54
Publish the Manuscript Online
2021-12-14 23:58
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Basic Study
Article Title BRAFV600E mutant colorectal cancer cells mediate local immunosuppressive microenvironment through exosomal long noncoding RNAs
Manuscript Source Unsolicited Manuscript
All Author List Jie Zhi, Xiao-jing Jia, Jing Yan, Hui-Cong Wang, Bo Feng, Han-Ying Xing and Yi-Tao Jia
ORCID
Author(s) ORCID Number
Jie Zhi http://orcid.org/0000-0003-1727-7746
Xiao-jing Jia http://orcid.org/0000-0003-1783-1292
Jing Yan http://orcid.org/0000-0002-0082-2747
Hui-Cong Wang http://orcid.org/0000-0003-2023-5176
Bo Feng http://orcid.org/0000-0002-5758-9130
Han-Ying Xing http://orcid.org/0000-0002-0337-9541
Yi-Tao Jia http://orcid.org/0000-0003-2610-9330
Funding Agency and Grant Number
Corresponding Author Yi-Tao Jia, MD, Professor, Department of Oncology, Hebei General Hospital, No. 348 Heping West Road, Shijiazhuang 050051, Hebei Province, China. jiayitao99@163.com
Key Words Colorectal cancer; BRAFV600E mutant; Exosome; Long noncoding RNA; Immunosuppressive microenvironment
Core Tip This study revealed that BRAFV600E mutant colorectal cancer (CRC) cells could lead to more angiogenesis and lymphoangiogenesis in the microenvironment by releasing exosomal long noncoding RNAs, inducing the formation of an immunosuppressive microenvironment. Our findings provide a hypothesis for finding new therapeutic strategies for BRAFV600E mutant CRC.
Publish Date 2021-12-14 23:58
Citation Zhi J, Jia XJ, Yan J, Wang HC, Feng B, Xing HY, Jia YT. BRAFV600E mutant colorectal cancer cells mediate local immunosuppressive microenvironment through exosomal long noncoding RNAs. World J Gastrointest Oncol 2021; 13(12): 2129-2148
URL https://www.wjgnet.com/1948-5204/full/v13/i12/2129.htm
DOI https://dx.doi.org/10.4251/wjgo.v13.i12.2129
Full Article (PDF) WJGO-13-2129.pdf
Full Article (Word) WJGO-13-2129.docx
Manuscript File 69684_Auto_Edited-CCG-WangTQ.docx
Answering Reviewers 69684-Answering reviewers.pdf
Audio Core Tip 69684-Audio core tip.m4a
Biostatistics Review Certificate 69684-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 69684-Conflict-of-interest statement.pdf
Copyright License Agreement 69684-Copyright license agreement.pdf
Institutional Review Board Approval Form or Document 69684-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 69684-Language certificate.pdf
Peer-review Report 69684-Peer-review(s).pdf
Scientific Editor Work List 69684-Scientific editor work list.pdf