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Articles Published Processes
8/26/2014 11:43:00 AM | Browse: 987 | Download: 1021
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Received |
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2013-10-31 11:33 |
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Peer-Review Started |
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2013-10-31 20:20 |
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To Make the First Decision |
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2013-12-16 17:31 |
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Return for Revision |
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2013-12-17 19:44 |
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Revised |
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2014-01-16 13:31 |
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Second Decision |
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2014-04-09 09:20 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-04-09 11:01 |
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Articles in Press |
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2014-05-23 09:25 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2014-04-29 16:37 |
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Typeset the Manuscript |
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2014-06-06 16:32 |
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Publish the Manuscript Online |
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2014-07-03 15:30 |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Retrospective Study |
Article Title |
Baseline HBsAg predicts response to pegylated interferon-α2b in HBeAg-positive chronic hepatitis B patients
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Manuscript Source |
Invited Manuscript |
All Author List |
Gong-Ying Chen, Meng-Fei Zhu, Da-Liang Zheng, Yan-Ting Bao, Jie Wang, Xiang Zhou and Guo-Qiang Lou |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Natural Science Foundation of Zhejiang Province, China |
Y210435 |
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Corresponding Author |
Dr. Guo-Qiang Lou, Hospital Affiliated to Hangzhou Normal University, 126 Wenzhou Road, Hangzhou 310015, Zhejiang Province, China. louguoqiang2008@126.com |
Key Words |
Chronic hepatitis B; Hepatitis B surface antigen; Baseline; Virological response; Pegylated interferon-α2b |
Core Tip |
The response to antiviral therapy in chronic hepatitis B (CHB) patients varies significantly among individuals. This retrospective study of 55 patients evaluated the predictive effect of baseline hepatitis B surface antigen (HBsAg) on virological response in HBeAg-positive CHB patients treated with pegylated interferon (PEG-IFN)-α2b. The results suggest that baseline HBsAg level in combination with HBV DNA quantitative values may become an effective predictor for guiding optimal therapy with PEG-IFN-α2b against HBeAg-positive CHB. |
Publish Date |
2014-07-03 15:30 |
Citation |
Chen GY, Zhu MF, Zheng DL, Bao YT, Wang J, Zhou X, Lou GQ. Baseline HBsAg predicts response to pegylated interferon-α2b in HBeAg-positive chronic hepatitis B. World J Gastroenterol 2014; 20(25): 8195-8200 |
URL |
http://www.wjgnet.com/1007-9327/full/v20/i25/8195.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v20.i25.8195 |
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