| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cardiac & Cardiovascular Systems |
| Manuscript Type |
Case Control Study |
| Article Title |
Associations between coagulation factor XII, coagulation factor XI, and stability of venous thromboembolism: A case-control study
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yan Meng, You Li, Yan-Jun Ye, Qiang Ma, Jun-Bo Zhang, Hao Qin, Yang-Yang Deng and Hong-Yan Tian |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Key Research and Development Program Project of Shannxi Province |
2017SF-254 |
|
| Corresponding Author |
Hong-Yan Tian, MD, Director, Director, Department of Peripheral Vascular Diseases, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277 Yanta Road, Xi'an 710061, Shannxi Province, China. hongyantian417@163.com |
| Key Words |
Case-control study; Deep venous thrombosis; Factor XI; Factor XII; Pulmonary embolism |
| Core Tip |
In this case-control study, we found that plasma level of factor XI (FXI:Ag) was significantly higher in patients with deep venous thrombosis (DVT), and pulmonary embolism (PE) compared with those with only DVT. In addition, using the 95th percentile of FXI:Ag as cut-off values, a higher plasma level of FXI:Ag was associated with unstable DVT, as shown by the prevalence of PE in patients with DVT. Since the majority of PE is caused by thrombus that falls out from unstable DVT, these findings might suggest that a higher plasma level of FXI:Ag could be a marker for unstable DVT. |
| Publish Date |
2022-03-22 14:34 |
| Citation |
Meng Y, Li Y, Ye YJ, Ma Q, Zhang JB, Qin H, Deng YY, Tian HY. Associations between coagulation factor XII, coagulation factor XI, and stability of venous thromboembolism: A case-control study. World J Clin Cases 2022; 10(9): 2700-2709 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i9/2700.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i9.2700 |
