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1/25/2022 9:22:03 AM | Browse: 347 | Download: 754
Publication Name World Journal of Gastroenterology
Manuscript ID 69913
Country/Territory China
Received
2021-07-21 14:34
Peer-Review Started
2021-07-21 14:38
To Make the First Decision
Return for Revision
2021-10-03 06:53
Revised
2021-10-16 16:00
Second Decision
2022-01-06 03:31
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-01-06 18:46
Articles in Press
2022-01-06 18:46
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-12-11 19:57
Typeset the Manuscript
2022-01-24 02:31
Publish the Manuscript Online
2022-01-25 09:22
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Effect of Bacillus subtilis, Enterococcus faecium, and Enterococcus faecalis supernatants on serotonin transporter expression in cells and tissues
Manuscript Source Unsolicited Manuscript
All Author List Yi-Ming Chen, Ying Li, Xin Wang, Ze-Lan Wang, Jun-Jie Hou, Shuai Su, Wei-Long Zhong, Xin Xu, Jie Zhang, Bang-Mao Wang and Yu-Ming Wang
ORCID
Author(s) ORCID Number
Yi-Ming Chen http://orcid.org/0000-0001-9793-7876
Ying Li http://orcid.org/0000-0002-7887-108X
Xin Wang http://orcid.org/0000-0002-4727-1612
Ze-Lan Wang http://orcid.org/0000-0002-2298-1968
Jun-Jie Hou http://orcid.org/0000-0002-8129-5618
Shuai Su http://orcid.org/0000-0002-2012-9704
Wei-Long Zhong http://orcid.org/0000-0002-7139-169X
Xin Xu http://orcid.org/0000-0001-8083-0095
Jie Zhang http://orcid.org/0000-0002-8100-5369
Bang-Mao Wang http://orcid.org/0000-0002-4702-9711
Yu-Ming Wang http://orcid.org/0000-0002-0392-1150
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China (General Program) 81570489
Youth Project of National Natural Science Foundation of China 81900487
Corresponding Author Yu-Ming Wang, MD, Chief Doctor, Department of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, 154 Anshan Road Heping District Tianjin, Tianjin 300052, China. yumingwangbest@163.com
Key Words Bacillus subtilis supernatant; Enterococcus faecalis supernatant; Enterococcus faecium supernatant; Serotonin transporter expression; Irritable bowel syndrome
Core Tip Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder that can cause chronic symptoms and changes in bowel habits. Serotonin and serotonin transporter (SERT) play significant roles in the development of IBS. Bacillus subtilis (B. subtilis), Enterococcus faecium (E. faecium), and Enterococcus faecalis (E. faecalis) are probiotics that are widely used in the clinical treatment of IBS. Here, we explored the effects of B. subtilis, E. faecium, and E. faecalis supernatants on the mRNA and protein expression of SERT in vitro and in vivo, highlighting the significance of the regulation of SERT expression in the treatment of IBS patients.
Publish Date 2022-01-25 09:22
Citation Chen YM, Li Y, Wang X, Wang ZL, Hou JJ, Su S, Zhong WL, Xu X, Zhang J, Wang BM, Wang YM. Effect of Bacillus subtilis, Enterococcus faecium, and Enterococcus faecalis supernatants on serotonin transporter expression in cells and tissues. World J Gastroenterol 2022; 28(5): 532-546
URL https://www.wjgnet.com/1007-9327/full/v28/i5/532.htm
DOI https://dx.doi.org/10.3748/wjg.v28.i5.532
Full Article (PDF) WJG-28-532.pdf
Full Article (Word) WJG-28-532.docx
Manuscript File 69913_Auto_Edited-LLW-Filipodia.docx
Answering Reviewers 69913-Answering reviewers.pdf
Audio Core Tip 69913-Audio core tip.mp3
Biostatistics Review Certificate 69913-Biostatistics Review Certificate.pdf
Conflict-of-Interest Disclosure Form 69913-Conflict-of-interest statement.pdf
Copyright License Agreement 69913-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 69913-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 69913-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 69913-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 69913-Language certificate.pdf
Peer-review Report 69913-Peer-review(s).pdf
Scientific Misconduct Check 69913-Bing-Wang LL-2.png
Scientific Editor Work List 69913-Scientific editor work list.pdf