Publication Name	World Journal of Stem Cells
Manuscript ID	6997
Country	Japan

Received	2013-10-31 15:00
Peer-Review Started	2013-10-31 19:46
To Make the First Decision	2013-11-19 13:02
Return for Revision	2013-11-20 18:27
Revised	2014-01-21 18:21
Second Decision	2014-02-20 20:03
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-02-20 20:17
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-03-16 01:22
Typeset the Manuscript	2014-04-20 15:05
Publish the Manuscript Online	2014-04-28 14:14

ISSN	1948-0210 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Cell Biology
Manuscript Type	Topic Highlights
Article Title	Umbilical cord-derived mesenchymal stem cells: Their advantages and potential clinical utility
Manuscript Source	Invited Manuscript
All Author List	Tokiko Nagamura-Inoue and Haiping He
Funding Agency and Grant Number
Corresponding Author	Tokiko Nagamura-Inoue, MD, PhD, Department of Cell Processing and Transfusion, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan. tokikoni@ims.u-tokyo.ac.jp
Key Words	Umbilical cord; Mesenchymal stem cells; Wharton’s Jelly; Multipotency; Immunotherapy
Core Tip	Human umbilical cord (UC) is a promising source of mesenchymal stem cells (MSCs). UC-MSCs have shown the ability of faster self-renewal and to differentiate into three germ layers, to accumulate in damaged tissue or inflamed regions, to promote tissue repair, and to modulate immune response. There are diverse protocols and culture methods for the isolation of MSCs from the various compartments of UC, such as Wharton’s jelly, vein, arteries, UC lining membrane and subamnion and perivascular regions. In this review, we introduce various compartments of UC and discuss the potential clinical utility of UC-MSCs for regenerative medicine and immunotherapy.
Publish Date	2014-04-28 14:14
Citation	Nagamura-Inoue T, He H. Umbilical cord-derived mesenchymal stem cells: Their advantages and potential clinical utility. World J Stem Cells 2014; 6(2): 195-202
URL	http://www.wjgnet.com/1948-0210/full/v6/i2/195.htm
DOI	http://dx.doi.org/10.4252/wjsc.v6.i2.195

Full Article (PDF)	WJSC-6-195.pdf
Full Article (Word)	WJSC-6-195.doc
Manuscript File	6997-Review.docx
Answering Reviewers	6997-Answering reviewers.pdf
Copyright License Agreement	6997-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	6997-Language certificate.pdf
Peer-review Report	6997-Peer review(s).pdf
Scientific Editor Work List	6997-Scientific editor work list.doc