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Articles Published Processes
8/23/2022 9:54:46 AM | Browse: 370 | Download: 718
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Received |
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2021-08-02 01:47 |
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Peer-Review Started |
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2021-08-02 01:51 |
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To Make the First Decision |
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Return for Revision |
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2021-11-10 14:35 |
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Revised |
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2021-12-23 14:22 |
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Second Decision |
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2022-07-21 03:10 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-07-26 17:55 |
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Articles in Press |
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2022-07-26 17:55 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-07-11 00:13 |
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Typeset the Manuscript |
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2022-08-17 09:36 |
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Publish the Manuscript Online |
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2022-08-23 09:54 |
| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Clinical and Translational Research |
| Article Title |
Eight hub genes as potential biomarkers for breast cancer diagnosis and prognosis: A TCGA-based study
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Nan Liu, Guo-Duo Zhang, Ping Bai, Li Su, Hao Tian and Miao He |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Hao Tian, MS, Surgeon, Department of Breast and Thyroid Surgery, Southwest Hospital, Army Medical University, No. 30 Gaotanyan Street, Shapingba District, Chongqing 400038, China. tianhao_cmu@163.com |
| Key Words |
Breast cancer; Bioinformatics; Hub gene; The Cancer Genome Atlas; Protein-protein interaction |
| Core Tip |
This study identified 1317 DEGs related to the occurrence and development of breast cancer (BC), 165 DEGs related to prognosis, and 8 hub genes (MAD2L1, PLK1, SAA1, CCNB1, SHCBP1, KIF4A, ANLN, and ERCC6L). Each of these eight hub genes has different expression levels in BC and is significantly related to prognosis. The results of this study indicate that studying these DEGs may help provide a full understanding of the molecular mechanisms underlying BC pathogenesis and progression. Moreover, these hub genes may serve as potential prognostic markers and therapeutic targets, which provide a reference for more in-depth and extensive prospective clinical research. |
| Publish Date |
2022-08-23 09:54 |
| Citation |
Liu N, Zhang GD, Bai P, Su L, Tian H, He M. Eight hub genes as potential biomarkers for breast cancer diagnosis and prognosis: A TCGA-based study. World J Clin Oncol 2022; 28(32): 4493-4507 |
| URL |
https://www.wjgnet.com/2218-4333/full/v13/i8/675.htm |
| DOI |
https://dx.doi.org/10.5306/wjco.v13.i8.675 |
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