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Articles Published Processes
6/9/2022 7:17:55 AM | Browse: 148 | Download: 336
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Received |
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2021-11-16 13:53 |
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Peer-Review Started |
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2021-11-16 13:54 |
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To Make the First Decision |
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Return for Revision |
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2022-02-14 08:02 |
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Revised |
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2022-02-24 18:11 |
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Second Decision |
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2022-03-29 02:02 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2022-04-04 03:36 |
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Articles in Press |
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2022-04-04 03:36 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-03-19 00:36 |
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Typeset the Manuscript |
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2022-05-04 06:50 |
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Publish the Manuscript Online |
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2022-06-09 07:17 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Hematology |
| Manuscript Type |
Case Report |
| Article Title |
Allogeneic stem cell transplantation-A curative treatment for paroxysmal nocturnal hemoglobinuria with PIGT mutation: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Laurence Schenone, Anne-Béatrice Notarantonio, Véronique Latger-Cannard, Veronique Fremeaux-Bacchi, Marcelo De Carvalho-Bittencourt, Marie-Thérèse Rubio, Marc Muller and Maud D'Aveni |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Maud D'Aveni, MD, PhD, Doctor, Hematology, CHRU Nancy, Allée du Morvan, Nancy F-54000, France. m.daveni-piney@chru-nancy.fr |
| Key Words |
Paroxysmal nocturnal hemoglobinuria; Allogeneic stem cell transplantation; PIGT mutation; Recurrent meningitidis; Autoinflammatory symptoms; Case report |
| Core Tip |
Paroxysmal nocturnal hemoglobinuria with autoinflammatory symptoms has been described in 4 cases with PIG-T mutations (PIGT-PNH entity). We report the fifth case in the world. For the first time we treated him with an allogeneic hematopoietic stem cell transplantation (allo-SCT) after repeated infusions of eculizumab to decrease autoinflammatory symptoms. Allo-SCT was performed with a mismatched unrelated donor and no excess of alloreactivity or toxicity was observed. We think that this new case report with a review of literature will help physicians to have a focus on PIGT-PNH. It suggests that allogeneic SCT should be considered as a curative treatment option for this disease. |
| Publish Date |
2022-06-09 07:17 |
| Citation |
Schenone L, Notarantonio AB, Latger-Cannard V, Fremeaux-Bacchi V, De Carvalho-Bittencourt M, Rubio MT, Muller M, D'Aveni M. Allogeneic stem cell transplantation-A curative treatment for paroxysmal nocturnal hemoglobinuria with PIGT mutation: A case report. World J Clin Cases 2022; 10(17): 5702-5707 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i17/5702.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i17.5702 |
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