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Articles Published Processes
1/25/2022 9:22:03 AM | Browse: 507 | Download: 1015
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Received |
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2021-07-26 11:04 |
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Peer-Review Started |
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2021-07-26 11:09 |
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To Make the First Decision |
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Return for Revision |
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2021-10-03 06:47 |
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Revised |
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2021-10-23 08:42 |
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Second Decision |
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2022-01-11 03:44 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-01-11 19:36 |
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Articles in Press |
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2022-01-11 19:36 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-01-08 21:25 |
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Typeset the Manuscript |
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2022-01-22 03:10 |
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Publish the Manuscript Online |
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2022-01-25 09:22 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Basic Study |
| Article Title |
Connective tissue growth factor expression hints at aggressive nature of colorectal cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ishrat Parveiz Bhat, Tahseen Bilal Rather, Irfan Maqbool, Gowhar Rashid, Kulsum Akhtar, Gulzar A Bhat, Fazl Q Parray, Besina Syed, Ishrat Younas Khan, Mohsin Kazi, Muhammad D Hussain and Mudassar Syed |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Sher-I-Kashmir Institute of Medical Sciences, Srinagar Kashmir, India |
SIMS/DF/17-467-73 |
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| Corresponding Author |
Mudassar Syed, PhD, Full Professor, Department of Clinical Biochemistry, Sher-I-Kashmir Institute of Medical Sciences, Soura Srinagar Kashmir, Srinagar 190011, Jammu and Kashmir, India. syed.mudassar@skims.ac.in |
| Key Words |
Connective tissue growth factor; Quantitative real time polymerase chain reaction; Immunohistochemistry; Western blotting; Colorectal cancer |
| Core Tip |
This study demonstrates that connective tissue growth factor is overexpressed in colorectal carcinoma and is predominantly localized in cytoplasm of the cell. The expression pattern of this gene showed a substantial association with aggressive phenotype of colorectal cancer like late-stage tumor and lymph node metastasis. It also showed a significant correlation with the overall and disease-free survival of colorectal cancer patients, hence could act as a predictive biomarker for diagnostics and prognostics of colorectal cancer. |
| Publish Date |
2022-01-25 09:22 |
| Citation |
Bhat IP, Rather TB, Maqbool I, Rashid G, Akhtar K, Bhat GA, Parray FQ, Syed B, Khan IY, Kazi M, Hussain MD, Syed M. Connective tissue growth factor expression hints at aggressive nature of colorectal cancer. World J Gastroenterol 2022; 28(5): 547-569 |
| URL |
https://www.wjgnet.com/1007-9327/full/v28/i5/547.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v28.i5.547 |
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