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1/25/2022 9:22:03 AM | Browse: 365 | Download: 576
Publication Name World Journal of Gastroenterology
Manuscript ID 70199
Country India
Received
2021-07-26 11:04
Peer-Review Started
2021-07-26 11:09
To Make the First Decision
Return for Revision
2021-10-03 06:47
Revised
2021-10-23 08:42
Second Decision
2022-01-11 03:44
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-01-11 19:36
Articles in Press
2022-01-11 19:36
Publication Fee Transferred
Edit the Manuscript by Language Editor
2022-01-08 21:25
Typeset the Manuscript
2022-01-22 03:10
Publish the Manuscript Online
2022-01-25 09:22
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Basic Study
Article Title Connective tissue growth factor expression hints at aggressive nature of colorectal cancer
Manuscript Source Unsolicited Manuscript
All Author List Ishrat Parveiz Bhat, Tahseen Bilal Rather, Irfan Maqbool, Gowhar Rashid, Kulsum Akhtar, Gulzar A Bhat, Fazl Q Parray, Besina Syed, Ishrat Younas Khan, Mohsin Kazi, Muhammad D Hussain and Mudassar Syed
ORCID
Author(s) ORCID Number
Ishrat Parveiz Bhat http://orcid.org/0000-0003-0663-6926
Tahseen Bilal Rather http://orcid.org/0000-0002-1363-6601
Irfan Maqbool http://orcid.org/0000-0003-1015-9536
Gowhar Rashid http://orcid.org/0000-0002-6321-3877
Kulsum Akhtar http://orcid.org/0000-0003-0546-4835
Gulzar A Bhat http://orcid.org/0000-0003-0653-9931
Fazl Q Parray http://orcid.org/0000-0003-3657-7808
Besina Syed http://orcid.org/0000-0001-9886-1113
Ishrat Younas Khan http://orcid.org/0000-0002-5179-5910
Mohsin Kazi http://orcid.org/0000-0002-5611-0378
Muhammad D Hussain http://orcid.org/0000-0003-1063-8203
Mudassar Syed http://orcid.org/0000-0001-9288-5077
Funding Agency and Grant Number
Funding Agency Grant Number
Sher-I-Kashmir Institute of Medical Sciences, Srinagar Kashmir, India SIMS/DF/17-467-73
Corresponding Author Mudassar Syed, PhD, Full Professor, Department of Clinical Biochemistry, Sher-I-Kashmir Institute of Medical Sciences, Soura Srinagar Kashmir, Srinagar 190011, Jammu and Kashmir, India. syed.mudassar@skims.ac.in
Key Words Connective tissue growth factor; Quantitative real time polymerase chain reaction; Immunohistochemistry; Western blotting; Colorectal cancer
Core Tip This study demonstrates that connective tissue growth factor is overexpressed in colorectal carcinoma and is predominantly localized in cytoplasm of the cell. The expression pattern of this gene showed a substantial association with aggressive phenotype of colorectal cancer like late-stage tumor and lymph node metastasis. It also showed a significant correlation with the overall and disease-free survival of colorectal cancer patients, hence could act as a predictive biomarker for diagnostics and prognostics of colorectal cancer.
Publish Date 2022-01-25 09:22
Citation Bhat IP, Rather TB, Maqbool I, Rashid G, Akhtar K, Bhat GA, Parray FQ, Syed B, Khan IY, Kazi M, Hussain MD, Syed M. Connective tissue growth factor expression hints at aggressive nature of colorectal cancer. World J Gastroenterol 2022; 28(5): 547-569
URL https://www.wjgnet.com/1007-9327/full/v28/i5/547.htm
DOI https://dx.doi.org/10.3748/wjg.v28.i5.547
Full Article (PDF) WJG-28-547.pdf
Full Article (Word) WJG-28-547.docx
Manuscript File 70199_Auto_Edited-JRF-Filipodia CL.docx
Answering Reviewers 70199-Answering reviewers.pdf
Audio Core Tip 70199-Audio core tip.m4a
Biostatistics Review Certificate 70199-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 70199-Conflict-of-interest statement.pdf
Copyright License Agreement 70199-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 70199-Grant application form(s).pdf
Institutional Review Board Approval Form or Document 70199-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 70199-Language certificate.pdf
Peer-review Report 70199-Peer-review(s).pdf
Scientific Misconduct Check 70199-Bing-Fan JR-2.png
Scientific Editor Work List 70199-Scientific editor work list.pdf