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Articles Published Processes
3/10/2022 12:08:49 PM | Browse: 435 | Download: 1253
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Received |
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2021-07-28 08:10 |
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Peer-Review Started |
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2021-07-28 08:14 |
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To Make the First Decision |
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Return for Revision |
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2021-09-06 01:29 |
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Revised |
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2021-09-10 05:28 |
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Second Decision |
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2022-01-21 05:44 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-01-23 03:48 |
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Articles in Press |
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2022-01-23 03:48 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-03-03 14:19 |
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Publish the Manuscript Online |
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2022-03-10 12:08 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
RNA-Seq profiling of circular RNAs in human colorectal cancer 5-fluorouracil resistance and potential biomarkers
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Pei-Qiu Cheng, Yu-Jing Liu, Sheng-An Zhang, Lu Lu, Wen-Jun Zhou, Dan Hu, Han-Chen Xu and Guang Ji |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81874206 |
| Shanghai Rising-Star Program |
20QA1409300 |
| the Program for Young Eastern Scholar at Shanghai Institutions of Higher Learning |
QD2019034 |
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| Corresponding Author |
Guang Ji, MD, PhD, Chief Doctor, Professor, Institute of Digestive Diseases, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, No. 725 South Wanping Road, Shanghai 200032, China. jiliver@vip.sina.com |
| Key Words |
Colorectal cancer; 5-Fluorouracil resistance; Circular RNAs; RNA sequencing; Network prediction; Biomarkers |
| Core Tip |
Therapy resistance has been a culprit for colorectal cancer (CRC) treatment. 5-fluorouracil is a first-line chemotherapeutic agent for CRC, and it is very important to reveal the potential biomarkers and mechanisms of resistance. Circular RNA (circRNA) plays a key role in the occurrence and development of cancers, but its function in the process of drug resistance has not been widely revealed. In this study, through the construction of drug-resistant cell lines and high-throughput sequencing technology, we revealed the changes in the expression of circRNAs during the process of drug resistance, and searched for circRNAs that could predict the occurrence of drug resistance as potential biomarkers. |
| Publish Date |
2022-03-10 12:08 |
| Citation |
Cheng PQ, Liu YJ, Zhang S, Lu L, Zhou WJ, Hu D, Xu HC, Ji G. RNA-Seq profiling of circular RNAs in human colorectal cancer 5-fluorouracil resistance and potential biomarkers. World J Gastrointest Oncol 2022; 14(3): 678-689 |
| URL |
https://www.wjgnet.com/1948-5204/full/v14/i3/678.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v14.i3.678 |
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