Publication Name	World Journal of Gastroenterology
Manuscript ID	7027
Country	China

Received	2013-11-02 12:58
Peer-Review Started	2013-11-02 20:40
To Make the First Decision	2014-01-09 18:22
Return for Revision	2014-01-16 22:52
Revised	2014-02-10 09:49
Second Decision	2014-03-05 14:19
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-03-05 15:17
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-03-30 17:54
Typeset the Manuscript	2014-04-19 19:50
Publish the Manuscript Online	2014-05-07 10:10

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Observational Study
Article Title	TNM staging of colorectal cancer should be reconsidered by T stage weighting
Manuscript Source	Invited Manuscript
All Author List	Jun Li, Bao-Cai Guo, Li-Rong Sun, Jian-Wei Wang, Xian-Hua Fu, Su-Zhan Zhang, Graeme Poston and Ke-Feng Ding
Funding Agency and Grant Number
Corresponding Author	Ke-Feng Ding, Professor, Department of Surgical Oncology, Second Affiliated Hospital, and The Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, Zhejiang University College of Medicine, No. 88 Jiefang Road, Hangzhou 310009, Zhejiang Province, China. dingkefeng@zju.edu.cn
Key Words	Colorectal cancer; Neoplasm staging; Cluster analysis; Survival analysis; Observational study
Core Tip	The 7th edition of the American Joint Committee on Cancer (AJCC) tumor node metastasis (TNM) staging system for colorectal cancer can not predict survival linearly by stage. We propose that the T stage has greater weight than the N stage, more especially in rectal cancer than in colon cancer. Moreover, in this article, we propose a revised scheme for the 7th edition of the AJCC TNM staging system. In our revised scheme, T4bN0 is classified to stage Ⅲa in colon cancer, but to stage Ⅲb in rectal cancer. This is the first attempt to revise the established TNM staging system for colorectal cancer by shaking the keystone of present classification based on the lymph nodes status.
Publish Date	2014-05-07 10:10
Citation	Li J, Guo BC, Sun LR, Wang JW, Fu XH, Zhang SZ, Poston G, Ding KF. TNM staging of colorectal cancer should be reconsidered by T stage weighting. World J Gastroenterol 2014; 20(17): 5104-5112
URL	http://www.wjgnet.com/1007-9327/full/v20/i17/5104.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i17.5104

Full Article (PDF)	WJG-20-5104.pdf
Full Article (Word)	WJG-20-5104.doc
Manuscript File	7027-Review.doc
Answering Reviewers	7027-Answering reviewers.pdf
Copyright License Agreement	7027-Copyright assignment.pdf
Peer-review Report	7027-Peer review(s).pdf
Scientific Editor Work List	7027-Scientific editor work list.doc