| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Predictive value of alarm symptoms in Rome IV irritable bowel syndrome: A multicenter cross-sectional study
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Qian Yang, Zhong-Cao Wei, Na Liu, Yang-Lin Pan, Xiao-Sa Jiang, Xin-Xing Tantai, Qi Yang, Juan Yang, Jing-Jie Wang, Lei Shang, Qiang Lin, Cai-Lan Xiao and Jin-Hai Wang |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the Key Research and Development Program of Shaanxi Province |
2017ZDXM-SF-046 |
|
| Corresponding Author |
Jin-Hai Wang, MD, Professor, Department of Gastroenterology, The Second Affiliated Hospital, Xi’an Jiaotong University, No. 157 Xiwu Road, Xi’an 710004, Shaanxi Province, China. jinhaiwang@hotmail.com |
| Key Words |
Alarm symptom; Irritable bowel syndrome; Predictive value; Rome IV; Organic disease |
| Core Tip |
The diagnosis of irritable bowel syndrome (IBS) depends on symptom-based criteria, but the accuracy of these criteria is poor. For suspected IBS patients meeting the Rome IV criteria, considering alarm symptoms does not significantly improve the positive predictive value for diagnosing IBS. However, alarm symptoms can help identify patients with organic disease; in particular, fecal occult blood, unintended weight loss and anemia have a high predictive value for organic disease. The presence of those alarm symptoms suggests that further examination may be needed, but they are not recommended as exclusion criteria for IBS. |
| Publish Date |
2022-01-12 04:01 |
| Citation |
Yang Q, Wei ZC, Liu N, Pan YL, Jiang XS, Tantai XX, Yang Q, Yang J, Wang JJ, Shang L, Lin Q, Xiao CL, Wang JH. Predictive value of alarm symptoms in Rome IV irritable bowel syndrome: A multicenter cross-sectional study. World J Clin Cases 2022; 10(2): 563-575 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i2/563.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i2.563 |
