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Articles Published Processes
2/11/2022 5:55:19 AM | Browse: 441 | Download: 976
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Received |
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2021-11-14 08:32 |
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Peer-Review Started |
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2021-11-14 08:32 |
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To Make the First Decision |
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Return for Revision |
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2021-12-09 06:47 |
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Revised |
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2021-12-27 07:41 |
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Second Decision |
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2022-01-10 05:42 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-01-10 22:09 |
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Articles in Press |
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2022-01-10 22:09 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-01-24 10:43 |
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Publish the Manuscript Online |
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2022-02-11 05:55 |
ISSN |
2307-8960 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Endocrinology & Metabolism |
Manuscript Type |
Retrospective Study |
Article Title |
Significance of serum glucagon-like peptide-1 and matrix Gla protein levels in patients with diabetes and osteoporosis
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Fei-Fei Xie, Yu-Fang Zhang, Yan-Fang Hu, Yun-Yun Xie, Xiao-Ying Wang, Shu-Zhen Wang and Bao-Qiang Xie |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Jiangxi Provincial Health and Family Planning Commission “Science and Technology Plan” |
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Corresponding Author |
Bao-Qiang Xie, BM BCh, Chief Doctor, Department of Endocrinology, Guangdong Provincial People's Hospital Ganzhou Hospital (Ganzhou Municipal Hospital), No. 49 Dagong Road, Zhanggong District, Ganzhou 341000, Jiangxi Province, China. xiebaoqiang1629@163.com |
Key Words |
Glucagon-like peptide-1; Matrix Gla protein; Diabetes mellitus; Osteoporosis; Bone mineral density; Systemic bone disease |
Core Tip |
Serum glucagon-like peptide-1 (GLP-1) and matrix Gla protein (MGP)levels were significantly positively correlated with bone mineral density values of the hip joint and lumbar vertebrae. They were significantly negatively correlated with type 1 procollagen amino-terminal propeptide, osteocalcin, and special sequence of carboxy-terminal peptide β of type 1 collagen. Older age and duration of diabetes were independent risk factors for osteoporosis for diabetic patients. Increased GLP-1 and MGP levels were protective factors against osteoporosis for diabetic patients. GLP-1 and MGP levels should be used as auxiliary evaluation indexes to evaluate the risk of osteoporosis for patients with diabetes to enable early detection of and intervention for diabetes with osteoporosis and improve its prognosis. |
Publish Date |
2022-02-11 05:55 |
Citation |
Xie FF, Zhang YF, Hu YF, Xie YY, Wang XY, Wang SZ, Xie BQ. Significance of serum glucagon-like peptide-1 and matrix Gla protein levels in patients with diabetes and osteoporosis. World J Clin Cases 2022; 10(5): 1527-1535 |
URL |
https://www.wjgnet.com/2307-8960/full/v10/i5/1527.htm |
DOI |
https://dx.doi.org/10.12998/wjcc.v10.i5.1527 |
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