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2/11/2022 5:55:19 AM | Browse: 308 | Download: 575
Publication Name World Journal of Clinical Cases
Manuscript ID 70411
Country China
Received
2021-11-14 08:32
Peer-Review Started
2021-11-14 08:32
To Make the First Decision
Return for Revision
2021-12-09 06:47
Revised
2021-12-27 07:41
Second Decision
2022-01-10 05:42
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-01-10 22:09
Articles in Press
2022-01-10 22:09
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-01-24 10:43
Publish the Manuscript Online
2022-02-11 05:55
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology & Metabolism
Manuscript Type Retrospective Study
Article Title Significance of serum glucagon-like peptide-1 and matrix Gla protein levels in patients with diabetes and osteoporosis
Manuscript Source Unsolicited Manuscript
All Author List Fei-Fei Xie, Yu-Fang Zhang, Yan-Fang Hu, Yun-Yun Xie, Xiao-Ying Wang, Shu-Zhen Wang and Bao-Qiang Xie
ORCID
Author(s) ORCID Number
Fei-Fei Xie http://orcid.org/0000-0002-9837-3045
Yu-Fang Zhang http://orcid.org/0000-0002-6711-8834
Yan-Fang Hu http://orcid.org/0000-0002-0980-7666
Yun-Yun Xie http://orcid.org/0000-0003-2662-747X
Xiao-Ying Wang http://orcid.org/0000-0001-7575-6046
Shu-Zhen Wang http://orcid.org/0000-0002-8491-0022
Bao-Qiang Xie http://orcid.org/0000-0002-7724-3380
Funding Agency and Grant Number
Funding Agency Grant Number
Jiangxi Provincial Health and Family Planning Commission “Science and Technology Plan”
Corresponding Author Bao-Qiang Xie, BM BCh, Chief Doctor, Department of Endocrinology, Guangdong Provincial People's Hospital Ganzhou Hospital (Ganzhou Municipal Hospital), No. 49 Dagong Road, Zhanggong District, Ganzhou 341000, Jiangxi Province, China. xiebaoqiang1629@163.com
Key Words Glucagon-like peptide-1; Matrix Gla protein; Diabetes mellitus; Osteoporosis; Bone mineral density; Systemic bone disease
Core Tip Serum glucagon-like peptide-1 (GLP-1) and matrix Gla protein (MGP)levels were significantly positively correlated with bone mineral density values of the hip joint and lumbar vertebrae. They were significantly negatively correlated with type 1 procollagen amino-terminal propeptide, osteocalcin, and special sequence of carboxy-terminal peptide β of type 1 collagen. Older age and duration of diabetes were independent risk factors for osteoporosis for diabetic patients. Increased GLP-1 and MGP levels were protective factors against osteoporosis for diabetic patients. GLP-1 and MGP levels should be used as auxiliary evaluation indexes to evaluate the risk of osteoporosis for patients with diabetes to enable early detection of and intervention for diabetes with osteoporosis and improve its prognosis.
Publish Date 2022-02-11 05:55
Citation Xie FF, Zhang YF, Hu YF, Xie YY, Wang XY, Wang SZ, Xie BQ. Significance of serum glucagon-like peptide-1 and matrix Gla protein levels in patients with diabetes and osteoporosis. World J Clin Cases 2022; 10(5): 1527-1535
URL https://www.wjgnet.com/2307-8960/full/v10/i5/1527.htm
DOI https://dx.doi.org/10.12998/wjcc.v10.i5.1527
Full Article (PDF) WJCC-10-1527.pdf
Full Article (Word) WJCC-10-1527.docx
Manuscript File 70411_Auto_Edited.docx
Answering Reviewers 70411-Answering reviewers.pdf
Audio Core Tip 70411-Audio core tip.m4a
Biostatistics Review Certificate 70411-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 70411-Conflict-of-interest statement.pdf
Copyright License Agreement 70411-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 70411-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 70411-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 70411-Language certificate.pdf
Peer-review Report 70411-Peer-review(s).pdf
Scientific Editor Work List 70411-Scientific editor work list.pdf