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Articles Published Processes
8/26/2014 2:46:00 PM | Browse: 1350 | Download: 1279
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Received |
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2013-11-02 14:50 |
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Peer-Review Started |
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2013-11-02 19:22 |
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To Make the First Decision |
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2014-01-15 17:41 |
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Return for Revision |
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2014-01-21 09:38 |
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Revised |
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2014-03-16 23:29 |
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Second Decision |
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2014-04-29 12:54 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-04-29 14:13 |
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Articles in Press |
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2014-05-23 11:04 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2014-05-16 17:20 |
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Typeset the Manuscript |
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2014-06-05 09:59 |
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Publish the Manuscript Online |
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2014-06-21 13:56 |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Topic Highlights |
Article Title |
Pathogenesis of liver cirrhosis
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Manuscript Source |
Invited Manuscript |
All Author List |
Wen-Ce Zhou, Quan-Bao Zhang and Liang Qiao |
Funding Agency and Grant Number |
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Corresponding Author |
Dr. Wen-Ce Zhou, Department of General Surgery II, the First Hospital of Lanzhou University, 1 Donggang Road, Lanzhou 730000, Gansu Province, China. zhouwc129@163.com |
Key Words |
Cirrhosis; Pathogenesis; Hepatic stellate cells; Cytokine; miRNA; Animal model; Therapy |
Core Tip |
Cirrhosis is the end-stage condition of many types of chronic liver diseases but the underlying mechanisms are far from being clarified. Multiple cellular and molecular factors might be involved in the initiation and progression of cirrhosis. Activation of hepatic stellate cells is a pivotal event in the development of cirrhosis. Animal models are crucial for understanding the pathogenesis and the development of more efficient therapeutic strategies for cirrhosis, with which cirrhosis may become a treatable or even a reversible disease. |
Publish Date |
2014-06-21 13:56 |
Citation |
Zhou WC, Zhang QB, Qiao L. Pathogenesis of liver cirrhosis. World J Gastroenterol 2014; 20(23): 7312-7324 |
URL |
http://www.wjgnet.com/1007-9327/full/v20/i23/7312.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v20.i23.7312 |
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