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Articles Published Processes
6/23/2022 2:39:01 PM | Browse: 354 | Download: 1004
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Received |
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2021-08-08 06:55 |
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Peer-Review Started |
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2021-08-08 06:59 |
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To Make the First Decision |
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Return for Revision |
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2021-11-11 08:37 |
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Revised |
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2021-11-18 15:15 |
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Second Decision |
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2022-05-24 03:20 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-05-28 07:15 |
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Articles in Press |
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2022-05-28 07:15 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-04-23 11:44 |
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Typeset the Manuscript |
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2022-05-30 09:21 |
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Publish the Manuscript Online |
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2022-06-23 14:39 |
ISSN |
1948-5182 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Meta-Analysis |
Article Title |
Efficacy and safety of sofosbuvir/velpatasvir with or without ribavirin in hepatitis C genotype 3 compensated cirrhosis: A meta-analysis
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Manuscript Source |
Invited Manuscript |
All Author List |
Jing Hong Loo, Wen Xin Flora Xu, Jun Teck Low, Wei Xuan Tay, Le Shaun Ang, Yew Chong Tam, Prem Harichander Thurairajah, Rahul Kumar and Yu Jun Wong |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Nurturing Clinician Scientist Scheme (NCCS) award by SingHealth Duke-NUS Academic Medical Centre and National Medical Research Council Singapore |
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Corresponding Author |
Yu Jun Wong, FRCP, MD, Consultant Physician-Scientist, Department of Gastroenterology and Hepatology, Changi General Hospital, Singhealth, 2, Simei Street 3, Singapore 529889, Singapore. eugene.wong.y.j@singhealth.com.sg |
Key Words |
Direct-acting antiviral; Hepatitis C; Cirrhosis; Sofosbuvir/velpatasvir |
Core Tip |
Ribavirin (RBV) as routine add-on therapy was not associated with higher sustained virological response in genotype 3 (GT3) compensated cirrhosis patients receiving sofosbuvir/velpatasvir (SOF/VEL), except in the subgroup of patients with baseline resistance-associated substitution mutation. As RBV is associated with a higher risk of treatment-related adverse event, RBV as routine add-on therapy to SOF/VEL should be reconsidered among compensated GT3 cirrhosis patients. |
Publish Date |
2022-06-23 14:39 |
Citation |
Loo JH, Xu WXF, Low JT, Tay WX, Ang LS, Tam YC, Thurairajah PH, Kumar R, Wong YJ. Efficacy and safety of sofosbuvir/velpatasvir with or without ribavirin in hepatitis C genotype 3 compensated cirrhosis: A meta-analysis. World J Hepatol 2022; 14(6): 1248-1257 |
URL |
https://www.wjgnet.com/1948-5182/full/v14/i6/1248.htm |
DOI |
https://dx.doi.org/10.4254/wjh.v14.i6.1248 |
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