Publication Name	World Journal of Hepatology
Manuscript ID	70598
Country	Singapore

Received	2021-08-08 06:55
Peer-Review Started	2021-08-08 06:59
To Make the First Decision
Return for Revision	2021-11-11 08:37
Revised	2021-11-18 15:15
Second Decision	2022-05-24 03:20
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-05-28 07:15
Articles in Press	2022-05-28 07:15
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-04-23 11:44
Typeset the Manuscript	2022-05-30 09:21
Publish the Manuscript Online	2022-06-23 14:39

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Meta-Analysis
Article Title	Efficacy and safety of sofosbuvir/velpatasvir with or without ribavirin in hepatitis C genotype 3 compensated cirrhosis: A meta-analysis
Manuscript Source	Invited Manuscript
All Author List	Jing Hong Loo, Wen Xin Flora Xu, Jun Teck Low, Wei Xuan Tay, Le Shaun Ang, Yew Chong Tam, Prem Harichander Thurairajah, Rahul Kumar and Yu Jun Wong
ORCID	Author(s) ORCID Number Jing Hong Loo http://orcid.org/0000-0002-2781-4245 Wen Xin Flora Xu http://orcid.org/0000-0003-4252-3689 Jun Teck Low http://orcid.org/0000-0002-0213-4008 Wei Xuan Tay http://orcid.org/0000-0001-5716-803X Le Shaun Ang http://orcid.org/0000-0003-3422-630X Yew Chong Tam http://orcid.org/0000-0002-3201-2634 Prem Harichander Thurairajah http://orcid.org/0000-0002-9411-1523 Rahul Kumar http://orcid.org/0000-0002-5092-4821 Yu Jun Wong http://orcid.org/0000-0002-0727-1183
Funding Agency and Grant Number	Funding Agency Grant Number Nurturing Clinician Scientist Scheme (NCCS) award by SingHealth Duke-NUS Academic Medical Centre and National Medical Research Council Singapore
Corresponding Author	Yu Jun Wong, FRCP, MD, Consultant Physician-Scientist, Department of Gastroenterology and Hepatology, Changi General Hospital, Singhealth, 2, Simei Street 3, Singapore 529889, Singapore. eugene.wong.y.j@singhealth.com.sg
Key Words	Direct-acting antiviral; Hepatitis C; Cirrhosis; Sofosbuvir/velpatasvir
Core Tip	Ribavirin (RBV) as routine add-on therapy was not associated with higher sustained virological response in genotype 3 (GT3) compensated cirrhosis patients receiving sofosbuvir/velpatasvir (SOF/VEL), except in the subgroup of patients with baseline resistance-associated substitution mutation. As RBV is associated with a higher risk of treatment-related adverse event, RBV as routine add-on therapy to SOF/VEL should be reconsidered among compensated GT3 cirrhosis patients.
Publish Date	2022-06-23 14:39
Citation	Loo JH, Xu WXF, Low JT, Tay WX, Ang LS, Tam YC, Thurairajah PH, Kumar R, Wong YJ. Efficacy and safety of sofosbuvir/velpatasvir with or without ribavirin in hepatitis C genotype 3 compensated cirrhosis: A meta-analysis. World J Hepatol 2022; 14(6): 1248-1257
URL	https://www.wjgnet.com/1948-5182/full/v14/i6/1248.htm
DOI	https://dx.doi.org/10.4254/wjh.v14.i6.1248

Full Article (PDF)	WJH-14-1248.pdf
Full Article (Word)	WJH-14-1248.docx
PRISMA 2009 Checklist	70598-PRISMA-2009-Checklist-revision.docx
Manuscript File	70598_Auto_Edited-LS.docx
Answering Reviewers	70598-Answering reviewers.pdf
Audio Core Tip	70598-Audio core tip.mp3
Biostatistics Review Certificate	70598-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	70598-Conflict-of-interest statement.pdf
Copyright License Agreement	70598-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	70598-Grant application form(s).PDF
Non-Native Speakers of English Editing Certificate	70598-Language certificate.pdf
Supplementary Material	70598-Supplementary material.pdf
Peer-review Report	70598-Peer-review(s).pdf
Scientific Editor Work List	70598-Scientific editor work list.pdf