BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
8/27/2014 3:47:00 PM | Browse: 586 | Download: 775
Publication Name World Journal of Anesthesiology
Manuscript ID 7066
Country/Territory Italy
Received
2013-11-02 15:44
Peer-Review Started
2013-11-04 19:34
To Make the First Decision
2013-11-19 12:55
Return for Revision
2013-11-19 16:02
Revised
2013-12-10 19:13
Second Decision
2013-12-19 13:02
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-12-19 13:28
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
2013-12-27 22:36
Typeset the Manuscript
2014-03-10 16:28
Publish the Manuscript Online
2014-03-11 12:20
ISSN 2218-6182 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Anesthesiology
Manuscript Type Letter to the Editor
Article Title Dexmedetomidine vs propofol in intensive care unit patients
Manuscript Source Invited Manuscript
All Author List Valeria Fadda, Dario Maratea, Sabrina Trippoli and Andrea Messori
Funding Agency and Grant Number
Corresponding Author Dr. Andrea Messori, HTA Unit, Area Vasta Centro Toscana, Regional Health System, Via San Salvi 12, 50100 Firenze, Italy. andrea.messori.it@gmail.com
Key Words Dexmedetomidine; Propofol; Midazolam; Sedation; Intensive care unit; Mechanical ventilation; Hospital stay; Meta-analysis; Trial sequential analysis
Core Tip Dexmedetomidine, a sedative agent for critically ill patients, has been studied in several randomized trials and in two meta-analyses. The clinical results were conflicting because of the diversity of the end-points and the small size of most studies. Since trial sequential analysis can improve the interpretation of controversial meta-analyses, we applied this technique to dexmedetomidine. According to our results, the comparison of dexmedetomidine vs propofol showed no proof of incremental effectiveness (for length of intensive care unit (ICU) stay and incidence of delirium) or of no incremental effectiveness (for duration of mechanical ventilation). Hence, the therapeutic role of dexmedetomidine in ICU is still uncertain.
Publish Date 2014-03-11 12:20
Citation Fadda V, Maratea D, Trippoli S, Messori A. Dexmedetomidine vs propofol in intensive care unit patients. World J Anesthesiol 2014; 3(1): 134-136 Available from: URL: http://www.wjgnet. com/2218-6182/full/v3/i1/134.htm DOI: http://dx.doi. org/10.5313/wja.v3.i1.134
URL http://www.wjgnet.com/2218-6182/full/v3/i1/134.htm
DOI http://dx.doi.org/10.5313/wja.v3.i1.134
Full Article (PDF) WJA-3-134.pdf
Full Article (Word) WJA-3-134.doc
Manuscript File 7066-Review.doc
Answering Reviewers 7066-Answering reviewers.pdf
Copyright License Agreement 7066-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 7066-Language certificate.pdf
Peer-review Report 7066-Peer review(s).pdf
Scientific Editor Work List 7066-Scientific editor work list.doc