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Articles Published Processes
3/22/2022 2:35:00 PM | Browse: 417 | Download: 899
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Received |
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2021-08-16 13:02 |
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Peer-Review Started |
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2021-08-16 13:05 |
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To Make the First Decision |
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Return for Revision |
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2021-11-06 07:30 |
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Revised |
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2021-11-17 02:03 |
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Second Decision |
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2022-02-15 03:19 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-02-16 07:01 |
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Articles in Press |
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2022-02-16 07:01 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-02-02 05:52 |
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Typeset the Manuscript |
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2022-02-25 02:39 |
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Publish the Manuscript Online |
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2022-03-22 14:35 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Case Report |
| Article Title |
Sequential occurrence of T790M mutation and small cell lung cancer transformation in EGFR-positive lung adenocarcinoma: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Er Hong, Xi-Er Chen, Jia Mao, Jing-Jing Zhou, Ling Chen, Jia-Yi Xu and Wei Tao |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Wei Tao, MD, Chief Doctor, Department of Radiology, Ningbo Municipal Hospital of Traditional Chinese Medicine, Affiliated to Zhejiang Chinese Medical University, <label>∗</label>Correspondence: Wei Tao, Department of Radiology, Ningbo Municipal Hospital of TCM, No. 819 Liyuan North Road, Haishu District, Ningbo 315000, China (e-mail: <email>70225027@qq.com</email>)., Ningbo 315000, Zhejiang Province, China. 70225027@qq.com |
| Key Words |
Adenocarcinoma; Epidermal growth factor receptor-tyrosine kinase inhibitor; Epidermal growth factor receptor-T790M mutation; Small cell lung cancer transformation; Chemotherapy; Case report |
| Core Tip |
The emergence of secondary drug resistance seriously affects the efficacy of tyrosine kinase inhibitor (TKI) treatment and prognosis of patients with epidermal growth factor receptor (EGFR) -mutated non-small cell lung cancer (NSCLC). EGFR-T790M mutation and tumor phenotype transformation are common drug resistance mechanisms in the first-generation TKI treatment process. Thus, it is necessary to determine the potential mechanisms using multiple biopsy methods with the aim of selecting appropriate and effective therapeutic drugs and extending the survival of patients with lung cancer. |
| Publish Date |
2022-03-22 14:35 |
| Citation |
Hong E, Chen XE, Mao J, Zhou JJ, Chen L, Xu JY, Tao W. Sequential occurrence of T790M mutation and small cell lung cancer transformation in EGFR-positive lung adenocarcinoma: A case report. World J Clin Cases 2022; 10(9): 2836-2843 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i9/2836.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i9.2836 |
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