BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
3/11/2022 12:39:21 AM | Browse: 360 | Download: 845
 |
Received |
|
2021-08-15 02:16 |
|
Peer-Review Started |
|
2021-08-15 02:21 |
 |
To Make the First Decision |
|
|
|
Return for Revision |
|
2021-10-20 20:50 |
|
Revised |
|
2021-10-30 13:49 |
|
Second Decision |
|
2022-01-25 03:47 |
|
Accepted by Journal Editor-in-Chief |
|
|
|
Accepted by Executive Editor-in-Chief |
|
2022-01-26 22:15 |
|
Articles in Press |
|
2022-01-26 22:15 |
|
Publication Fee Transferred |
|
|
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2022-02-19 14:56 |
|
Publish the Manuscript Online |
|
2022-03-11 00:39 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Geriatrics & Gerontology |
| Manuscript Type |
Case Report |
| Article Title |
Idarucizumab reverses dabigatran-induced anticoagulation in treatment of gastric bleeding: A case report
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yu Jia, Shao-Hua Wang, Na-Juan Cui, Quan-Xi Liu, Wei Wang, Xue Li, Ya-Mei Gu and Yan Zhu |
| ORCID |
|
| Funding Agency and Grant Number |
|
| Corresponding Author |
Yan Zhu, MS, Attending Doctor, gastroenterology, Hospital of Integrated Traditional Chinese and Western Medicine, No.3 East Yongding Road, Haidian District, Beijing 100039, China. zy815925@163.com |
| Key Words |
Idarucizumab; Dabigatran; Gastric bleeding; Atrial fibrillation; Case report |
| Core Tip |
The anticoagulatory effect of dabigatran resolves completely after five half-lives, which is approximately 2.5-3.5 d after the last dose for patients with normal renal function. Thrombin time (TT) is sensitive to the effects of dabigatran and can be prolonged even with trivial amounts of the drug. This patient exhibited persistent bleeding in the normal coagulation test (except for TT), possibly due to the anticoagulatory effects of the drug administered 4 days after the last dose for her renal insufficiency. Therefore, idarucizumab was administered for hemostasis, thus stopping the bleeding. This case highlights the importance of regular monitoring of renal function in older patients. |
| Publish Date |
2022-03-11 00:39 |
| Citation |
Jia Y, Wang SH, Cui NJ, Liu QX, Wang W, Li X, Gu YM, Zhu Y. Idarucizumab reverses dabigatran-induced anticoagulation in treatment of gastric bleeding: A case report. World J Clin Cases 2021; 10(8): 2537-2542 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i8/2537.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i8.2537 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
