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1/15/2022 12:57:35 PM | Browse: 237 | Download: 395
Publication Name World Journal of Clinical Cases
Manuscript ID 70794
Country China
Received
2021-08-18 08:22
Peer-Review Started
2021-08-18 08:24
To Make the First Decision
Return for Revision
2021-09-29 07:23
Revised
2021-10-13 12:10
Second Decision
2021-12-17 03:24
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-12-23 04:06
Articles in Press
2021-12-23 04:06
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-01-12 05:37
Publish the Manuscript Online
2022-01-15 12:57
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pathology
Manuscript Type Retrospective Study
Article Title Evaluating tumor-infiltrating lymphocytes in hepatocellular carcinoma using hematoxylin and eosin-stained tumor sections
Manuscript Source Unsolicited Manuscript
All Author List Min Du, Yu-Meng Cai, Yu-Lei Yin, Li Xiao and Yuan Ji
ORCID
Author(s) ORCID Number
Min Du http://orcid.org/0000-0003-2866-8873
Yu-Meng Cai http://orcid.org/0000-0001-7659-5125
Yu-Lei Yin http://orcid.org/0000-0003-4183-4178
Li Xiao http://orcid.org/0000-0002-8530-0584
Yuan Ji http://orcid.org/0000-0002-2631-9082
Funding Agency and Grant Number
Corresponding Author Yuan Ji, MD, Chief Doctor, Professor, Teacher, Department of Pathology, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Xuhui Area, Shanghai 200032, China. ji.yuan@zs-hospital.sh.cn
Key Words Lymphocytes; Tumor infiltration; Hepatocellular carcinoma; Hematoxylin and eosin-stained; Pathology
Core Tip Successful use of immunotherapy in tumors starve for widely applicable, accessible and reliable immune-oncology biomarkers. Assessing tumor infiltrating lymphocytes (TILs) in hematoxylin and eosin (H&E)-stained tissues showed great clinical validity and utility in many solid tumors. However, barely any research on hepatocellular carcinoma (HCC) has been published. TILs evaluated in H&E-stained HCC tissues showed a great prognostic effect for recurrence in the present study and might be helpful to select patients with the highest likelihood of responding to immunotherapeutic agents. The method has low requirements in terms of technical and economic costs and can be easily applied in routine practice.
Publish Date 2022-01-15 12:57
Citation Du M, Cai YM, Yin YL, Xiao L, Ji Y. Evaluating tumor-infiltrating lymphocytes in hepatocellular carcinoma using hematoxylin and eosin-stained tumor sections. World J Clin Cases 2022; 10(3): 856-869
URL https://www.wjgnet.com/2307-8960/full/v10/i3/856.htm
DOI https://dx.doi.org/10.12998/wjcc.v10.i3.856
Full Article (PDF) WJCC-10-856.pdf
Full Article (Word) WJCC-10-856.docx
Manuscript File 70794_Auto_Edited.docx
Answering Reviewers 70794-Answering reviewers.pdf
Audio Core Tip 70794-Audio core tip.mp3
Biostatistics Review Certificate 70794-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 70794-Conflict-of-interest statement.pdf
Copyright License Agreement 70794-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 70794-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 70794-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 70794-Language certificate.pdf
Supplementary Material 70794-Supplementary material.pdf
Peer-review Report 70794-Peer-review(s).pdf
Scientific Misconduct Check 70794-Bing-Wang JJ-2.png
Scientific Editor Work List 70794-Scientific editor work list.pdf