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Articles Published Processes
1/15/2022 12:57:35 PM | Browse: 345 | Download: 994
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Received |
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2021-08-17 08:44 |
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Peer-Review Started |
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2021-08-17 08:48 |
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To Make the First Decision |
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Return for Revision |
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2021-11-09 12:09 |
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Revised |
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2021-11-17 14:44 |
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Second Decision |
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2021-12-20 03:27 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-12-23 04:08 |
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Articles in Press |
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2021-12-23 04:08 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-01-12 05:30 |
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Publish the Manuscript Online |
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2022-01-15 12:57 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
High tumor mutation burden indicates a poor prognosis in patients with intrahepatic cholangiocarcinoma
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jian-Ping Song, Xue-Zhi Liu, Qian Chen and Yan-Feng Liu |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Shandong Scientific and Technological Research Program |
2019GSF108254 |
| Shandong Natural Science Foundation |
ZR2021MH339 |
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| Corresponding Author |
Yan-Feng Liu, FRSC, MD, PhD, Doctor, Doctor, Department of Hepatobiliary Surgery, Qilu Hospital of Shandong University, No. 107 Wenhua Xi Road, Jinan 250012, Shandong Province, China. liu19822012@163.com |
| Key Words |
Tumor mutation burden; Intrahepatic cholangiocarcinoma; Prognosis; Nomogram |
| Core Tip |
We analyzed the data of 412 patients with intrahepatic cholangiocarcinoma (ICC) from the Memorial Sloan Kettering Cancer Center cohort in the study. ICC patients with high tumor mutation burden (TMB) indicated a poor overall survival (OS) and relapse free survival compared with those with those with low TMB. Cox regression analysis of patient OS also demonstrated that TMB was an independent risk predictor for ICC. The nomogram and calibration curve also indicated the effectiveness of the constructed prognostic model. |
| Publish Date |
2022-01-15 12:57 |
| Citation |
Song JP, Liu XZ, Chen Q, Liu YF. High tumor mutation burden indicates a poor prognosis in patients with intrahepatic cholangiocarcinoma. World J Clin Cases 2022; 10(3): 790-801 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i3/790.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i3.790 |
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