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12/28/2021 9:18:59 AM | Browse: 233 | Download: 403
Publication Name World Journal of Meta-Analysis
Manuscript ID 70877
Country China
Received
2021-08-18 04:44
Peer-Review Started
2021-08-18 04:48
To Make the First Decision
Return for Revision
2021-11-06 07:59
Revised
2021-11-13 17:54
Second Decision
2021-12-24 04:45
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-12-24 08:20
Articles in Press
2021-12-24 08:20
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-12-14 10:02
Typeset the Manuscript
2021-12-26 15:41
Publish the Manuscript Online
2021-12-28 09:18
ISSN 2308-3840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Clinical Neurology
Manuscript Type Meta-Analysis
Article Title Efficacy and safety of fingolimod in stroke: A systemic review and meta-analysis
Manuscript Source Unsolicited Manuscript
All Author List Kai Zhao, Yu Guo, Ming-Fei Yang and Qiang Zhang
ORCID
Author(s) ORCID Number
Kai Zhao http://orcid.org/0000-0003-4456-3502
Yu Guo http://orcid.org/0000-0003-4456-3501
Ming-Fei Yang http://orcid.org/0000-0002-5109-6001
Qiang Zhang http://orcid.org/0000-0001-8665-8134
Funding Agency and Grant Number
Funding Agency Grant Number
Project of Science and Technology Department of Qinghai Province 2020-ZJ-774
National Key R&D Program of China 2018YFC1312601
Corresponding Author Qiang Zhang, MD, PhD, Chief Doctor, Surgeon, Department of Neurosurgery, Qinghai Provincial People's Hospital, No. 2 Gonghe Road, Xining 810007, Qinghai Province, China. zhangqiang691212@163.com
Key Words Acute ischemic stroke; Intracerebral hemorrhage; Fingolimod; Meta-analysis; Treatment
Core Tip Brain tissue injury in stroke patients involves inflammation around the infarction lesion or hematoma, which is an important reason for disease deterioration and can result in a poor prognosis. Our systemic review and meta-analysis of recent randomized controlled trials found that fingolimod might improve neurological function in stroke patients by reducing lymphocyte infiltration in the brain effectively; however, we did not find the evidence that fingolimod could promote infarction lesion or hematoma absorption. In general, oral fingolimod (0.5 mg/d, 3 consecutive days) was safe in stroke patients except for some rare severe adverse events.
Publish Date 2021-12-28 09:18
Citation Zhao K, Guo Y, Yang MF, Zhang Q. Efficacy and safety of fingolimod in stroke: A systemic review and meta-analysis. World J Meta-Anal 2021; 9(6): 585-597
URL https://www.wjgnet.com/2308-3840/full/v9/i6/585.htm
DOI https://dx.doi.org/10.13105/wjma.v9.i6.585
Full Article (PDF) WJMA-9-585.pdf
Full Article (Word) WJMA-9-585.docx
PRISMA 2009 Checklist 70877-PRISMA-2009-Checklist-revision.pdf
Manuscript File 70877_Auto_Edited-ML_WangTQ.docx
Answering Reviewers 70877-Answering reviewers.pdf
Audio Core Tip 70877-Audio core tip.mp3
Biostatistics Review Certificate 70877-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 70877-Conflict-of-interest statement.pdf
Copyright License Agreement 70877-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 70877-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 70877-Language certificate.pdf
Peer-review Report 70877-Peer-review(s).pdf
Scientific Misconduct Check 70877-Bing-Liu M-2.png
Scientific Editor Work List 70877-Scientific editor work list.pdf