Publication Name	World Journal of Hepatology
Manuscript ID	7092
Country	Mexico

Received	2013-11-03 21:02
Peer-Review Started	2013-11-04 11:07
To Make the First Decision	2013-12-25 18:07
Return for Revision	2013-12-31 14:27
Revised	2014-01-27 13:06
Second Decision	2014-02-20 20:01
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-02-20 20:13
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-03-13 11:46
Publish the Manuscript Online	2014-03-19 20:40

ISSN	1948-5182 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Hepatoprotective effect of silymarin
Manuscript Source	Invited Manuscript
All Author List	Nancy Vargas-Mendoza, Eduardo Madrigal-Santillán, Ángel Morales-González, Jaime Esquivel-Soto, Cesar Esquivel-Chirino, Manuel García-Luna y González-Rubio, Juan A Gayosso-de-Lucio and José A Morales-González
Funding Agency and Grant Number	Funding Agency Grant Number Proyecto SIP 20140856 ESM-IPN
Corresponding Author	José A Morales-González, MD, PhD, Laboratorio Medicina de Conservación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón, Col. Casco de Santo Tomás, Del. Miguel Hidalgo, México City 11340, México. jmorales101@yahoo.com.mx
Key Words	Silybum marianum; Hepatoprotector; Lipoperoxidation; Silymarin
Core Tip	One of the mechanisms of liver damage caused by alcohol is the generation of free radicals formed by the metabolism of this xenobiotic. Silymarin is an antioxidant that protects the liver from the free radical damage produced by alcohol metabolism. Silymarin is the most used natural compound for the treatment of hepatic diseases worldwide due to its antioxidant, anti-inflammatory, and anti-fibrotic activities. Silymarin functions by stabilizing biological membranes and increasing protein synthesis.
Publish Date	2014-03-19 20:40
Citation	Vargas-Mendoza N, Madrigal-Santillán E, Morales-González á, Esquivel-Soto J, Esquivel-Chirino C, García-Luna y González-Rubio M, Gayosso-de-Lucio JA, Morales-González JA. Hepatoprotective effect of silymarin. World J Hepatol 2014; 6(3): 144-149
URL	http://www.wjgnet.com/1948-5182/full/v6/i3/144.htm
DOI	http://dx.doi.org/10.4254/wjh.v6.i3.144

Full Article (PDF)	WJH-6-144.pdf
Manuscript File	7092-Review.doc
Answering Reviewers	7092-Answering reviewers.pdf
Copyright License Agreement	7092-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	7092-Language certificate.pdf
Peer-review Report	7092-Peer reviews.pdf
Scientific Editor Work List	7092-Scientific editor work list.doc