Publication Name	World Journal of Hepatology
Manuscript ID	7112
Country	Greece

Received	2013-11-05 10:41
Peer-Review Started	2013-11-05 16:07
To Make the First Decision	2013-12-25 18:20
Return for Revision	2014-01-06 11:29
Revised	2014-05-15 15:05
Second Decision
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-05-29 09:50
Articles in Press	2014-05-29 10:40
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-06-11 16:18
Typeset the Manuscript	2014-07-22 17:22
Publish the Manuscript Online	2014-07-25 16:43

ISSN	1948-5182 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Surgery
Manuscript Type	Clinical Trials Study
Article Title	Patients with multiple synchronous colonic cancer hepatic metastases benefit from enrolment in a “liver first” approach protocol
Manuscript Source	Invited Manuscript
All Author List	Dimitrios Kardassis, Achilleas Ntinas, Dimosthenis Miliaras, Alexandros Kofokotsios, Konstantinos Papazisis and Dionisios Vrochides
Funding Agency and Grant Number
Corresponding Author	Dimitrios Kardassis, MD, Centre for Hepato-Pancreato-Biliary Surgery, “Euromedica Geniki Kliniki” General Hospital, R.: 701, 11 Maria Callas Street, 54645 Thessaloniki, Greece. dimitrios.kardassis@gmx.net
Key Words	Clinical protocols; Colectomy; Colon cancer; Hepatectomy; Liver neoplasm
Core Tip	Complete tumour burden resection remains the only possible curative therapy for liver-limited colon cancer metastatic disease. However, there are different approaches regarding treatment of the primary tumour and its hepatic metastases, if the latter are synchronous and unresectable with one surgical procedure. For this subgroup of patients, a “liver first” approach protocol is introduced in order to assess standardised treatment as well as to prevent overtreatment in cases of undetected extra-hepatic metastatic dissemination or disease progression.
Publish Date	2014-07-25 16:43
Citation	Kardassis D, Ntinas A, Miliaras D, Kofokotsios A, Papazisis K, Vrochides D. Patients with multiple synchronous colonic cancer hepatic metastases benefit from enrolment in a “liver first” approach protocol. World J Hepatol 2014; 6(7): 513-519
URL	http://www.wjgnet.com/1948-5182/full/v6/i7/513.htm
DOI	http://dx.doi.org/10.4254/wjh.v6.i7.513

Full Article (PDF)	WJH-6-513.pdf
Full Article (Word)	WJH-6-513.doc
Manuscript File	7112-Review.docx
Answering Reviewers	7112-Answering reviewers.pdf
Copyright License Agreement	7112-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	7112-Language certificate.docx
Peer-review Report	7112-Peer review(s).pdf
Scientific Misconduct Check	7112-CrossCheck.jpg
Scientific Editor Work List	7112-Scientific editor work list.pdf