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Articles Published Processes
9/7/2014 1:30:00 PM | Browse: 1222 | Download: 1236
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Received |
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2013-11-05 11:10 |
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Peer-Review Started |
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2013-11-05 17:17 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2013-12-02 17:03 |
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Revised |
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2013-12-23 11:33 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2014-04-16 11:17 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2014-04-16 12:13 |
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Articles in Press |
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2014-05-23 10:59 |
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Edit the Manuscript by Language Editor |
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2014-05-14 08:30 |
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Typeset the Manuscript |
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2014-08-23 19:38 |
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Publish the Manuscript Online |
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2014-09-07 13:31 |
| Category |
Virology |
| Manuscript Type |
Topic Highlights |
| Article Title |
Control of hepatitis B virus replication by interferons and Toll-like receptor signaling pathways
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Rong-Juan Pei, Xin-Wen Chen and Meng-Ji Lu |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
31200135 (to Pei RJ and Chen XC) |
| National Natural Science Foundation of China |
31200699 (to Pei RJ and Chen XC) |
| German Research Foundation |
TRR60 (to Lu MG) |
| German Research Foundation |
GK1045/2 (to Lu MG) |
| German Research Foundation |
GK1949 (to Lu MG) |
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| Corresponding Author |
Meng-Ji Lu, Professor, Institute of Virology, University Hospital of Essen, Hufelandstrasse 55, 45122 Essen, Germany. mengji.lu@uni-due.de |
| Key Words |
Hepatitis B virus; Interferon; Toll-like receptor; Interferon stimulated genes; Innate immune response |
| Core Tip |
Hepatitis B virus (HBV) infection is one of the major causes of liver diseases affecting more than 350 million people worldwide. Interferon (IFN)- and Toll-like receptors (TLR)-mediated innate immune responses could restrict HBV replication at the different steps of viral life cycle. Though a great number of publications in this field appeared during the last years, there is no review to discuss the progress. Here, we summarized the currently available knowledge about the anti-HBV effect of IFNs and TLRs and the possible effectors downstream the IFN signaling pathway. This review provides an overview for scientists working on HBV and related fields. |
| Publish Date |
2014-09-07 13:31 |
| Citation |
Pei RJ, Chen XW, Lu MJ. Control of hepatitis B virus replication by interferons and Toll-like receptor signaling pathways. World J Gastroenterol 2014; 20(33): 11618-11629 |
| URL |
http://www.wjgnet.com/1007-9327/full/v20/i33/11618.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v20.i33.11618 |
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