| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Radiology, Nuclear Medicine & Medical Imaging |
| Manuscript Type |
Case Report |
| Article Title |
Langerhans cell histiocytosis presenting as an isolated brain tumour: A case report
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Han-Xiang Liang, Yue-Long Yang, Qing Zhang, Zhi Xie, En-Tao Liu and Shu-Xia Wang |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Guangdong Medical Research Fund to Han-Xiang Liang |
B2021084 |
| Traditional Chinese Medicine Bureau of Guangdong Province to En-Tao Liu |
20211005 |
| High-level Hospital Construction Research Project of Maoming People's Hospital to Han-Xiang Liang |
ZX2020014 |
|
| Corresponding Author |
En-Tao Liu, MD, Doctor, WeiLun PET Center, Department of Nuclear Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Room 526, 5/F, Weilun Building of Guangdong Provincial People's Hospital, No. 106 Zhongshan Er Road, Guangzhou 510080, Guangdong Province, China. liuentao@gdph.org.cn |
| Key Words |
Langerhans cell histiocytosis; Brain neoplasms; Lung; Computed tomography; Magnetic resonance imaging; Positron emission tomography/computed tomography; Case report |
| Core Tip |
Langerhans cell histiocytosis (LCH) is a rare hematological disease characterized by a clonal proliferation of abnormal langerhans cells. It can affect any organ or system, especially the bone, skin, lung, and central nervous system (CNS). In the CNS, the hypothalamic-pituitary is predominantly affected, whereas the brain parenchyma is rarely affected. Cases of LCH involving the brain parenchyma and presenting as an isolated brain tumour have been reported, but all the reports lack complete multimodal imaging. In this manuscript, we have reported a case of LCH involving the brain parenchyma and bilateral lungs, which was assessed using computed tomography (CT), high-resolution CT, magnetic resonance imaging, and 18F-fluorodeoxyglucose positron emission tomography/CT. Furthermore, we have reviewed the relevant literature. |
| Publish Date |
2022-01-24 08:11 |
| Citation |
Liang HX, Yang YL, Zhang Q, Xie Z, Liu ET, Wang SX. Langerhans cell histiocytosis presenting as an isolated brain tumour: A case report. World J Clin Cases 2022; 10(4): 1423-1431 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i4/1423.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i4.1423 |
