Publication Name	World Journal of Clinical Cases
Manuscript ID	71445
Country	China

Received	2021-09-08 02:54
Peer-Review Started	2021-09-08 02:55
To Make the First Decision
Return for Revision	2021-10-27 00:17
Revised	2021-11-05 07:48
Second Decision	2022-03-11 06:06
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-03-16 16:18
Articles in Press	2022-03-16 16:18
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-04-17 14:00
Publish the Manuscript Online	2022-04-30 05:08

ISSN	2307-8960 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Clinical Neurology
Manuscript Type	Case Report
Article Title	Paraneoplastic neurological syndrome with positive anti⁃Hu and anti-Yo antibodies: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Zi-Chao Li, Hong-Bin Cai, Zhen-Zhen Fan, Xiao-Bin Zhai and Zhao-Ming Ge
ORCID	Author(s) ORCID Number Zi-Chao Li http://orcid.org/0000-0003-3563-2377 Hong-Bin Cai http://orcid.org/0000-0003-3371-140X Zhen-Zhen Fan http://orcid.org/0000-0003-1251-2479 Xiao-Bin Zhai http://orcid.org/0000-0002-3971-7709 Zhao-Ming Ge http://orcid.org/0000-0002-4570-8657
Funding Agency and Grant Number
Corresponding Author	Zhao-Ming Ge, MD, Chief Doctor, Department of Neurology, Lanzhou University Second Hospital, No. 82 Cuiyingmen, Chengguan District, Lanzhou 730000, Gansu Province, China. gezhaoming123456@163.com
Key Words	Paraneoplastic syndrome; Anti-Hu antibody; Anti-Yo antibody; Small cell lung cancer; Breast cancer; Intravenous immunoglobulin.
Core Tip	Neurological paraneoplastic syndrome is a common manifestation in patients with tumors, and in some cases, it appears earlier than the tumor. We report a rare case in which two different paraneoplastic antibodies were present. While most previous studies have reported this syndrome due to one tumor, this patient presented with two different tumors and two paraneoplastic antibodies at the same time, causing neurological symptoms such as ataxia, limb numbness, and weakness. This case highlights the specificity of paraneoplastic antibodies to their corresponding tumors, avoiding a missed diagnosis when multiple antibodies are present and providing a reference for future clinical diagnosis.
Publish Date	2022-04-30 05:08
Citation	Li ZC, Cai HB, Fan ZZ, Zhai BX, Ge ZM. Paraneoplastic neurological syndrome with positive anti-Hu and anti-Yo antibodies: A case report. World J Clin Cases 2022; 10(13): 4190-4195
URL	https://www.wjgnet.com/2307-8960/full/v10/i13/4190.htm
DOI	https://dx.doi.org/10.12998/wjcc.v10.i13.4190

Full Article (PDF)	WJCC-10-4190.pdf
Full Article (Word)	WJCC-10-4190.docx
CARE Checklist–2016	71445-CARE-Checklist–2016-revision.pdf
Manuscript File	71445_Auto_Edited.docx
Answering Reviewers	71445-Answering reviewers.pdf
Audio Core Tip	71445-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	71445-Conflict-of-interest statement.pdf
Copyright License Agreement	71445-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	71445-Grant application form(s).pdf
Signed Consent for Treatment Form(s) or Document(s)	71445-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	71445-Language certificate.pdf
Peer-review Report	71445-Peer-review(s).pdf
Scientific Editor Work List	71445-Scientific editor work list.pdf
CrossCheck Report	71445-CrossCheck report.pdf