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Articles Published Processes
1/13/2022 11:55:40 AM | Browse: 566 | Download: 1063
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Received |
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2021-09-09 18:26 |
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Peer-Review Started |
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2021-09-09 18:29 |
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To Make the First Decision |
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Return for Revision |
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2021-10-16 03:37 |
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Revised |
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2021-10-19 10:57 |
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Second Decision |
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2022-01-05 03:28 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-01-06 18:44 |
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Articles in Press |
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2022-01-06 18:44 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-01-11 10:04 |
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Publish the Manuscript Online |
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2022-01-13 11:55 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Review |
Article Title |
Non-alcoholic fatty liver disease and hepatocellular carcinoma: Clinical challenges of an intriguing link
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Lampros Chrysavgis, Ilias Giannakodimos, Panagiota Diamantopoulou and Evangelos Cholongitas |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Evangelos Cholongitas, MD, PhD, Associate Professor, First Department of Internal Medicine, "Laiko" General Hospital of Athens, National and Kapodistrian University of Athens, Agiou Thoma 17, Athens 11527, Greece. cholongitas@yahoo.gr |
Key Words |
Non-alcoholic fatty liver disease; Hepatocellular carcinoma; Epidemiology; Risk factors; Surveillance; Risk stratification |
Core Tip |
Non-alcoholic fatty liver disease (NAFLD) is projected to emerge as the leading cause of hepatocellular carcinoma (HCC) worldwide. Demographic factors, genetic predisposition and behavioral parameters have been identified as independent risk factors for NAFLD-related HCC, which can arise even in the absence of cirrhosis. Currently, the most challenging issue for the scientific community worldwide is the identification of the pre-cirrhotic NAFLD patients who have increased risk for HCC. Noteworthy, the central concept for the surveillance policies in the near future should be the identification, via an individual, risk-assessment based precision screening of high-risk NAFLD patients, cirrhotic or not. |
Publish Date |
2022-01-13 11:55 |
Citation |
Chrysavgis L, Giannakodimos I, Diamantopoulou P, Cholongitas E. Non-alcoholic fatty liver disease and hepatocellular carcinoma: Clinical challenges of an intriguing link. World J Gastroenterol 2022; 28(3): 310-331 |
URL |
https://www.wjgnet.com/1007-9327/full/v28/i3/310.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v28.i3.310 |
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