| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Nomogram for predicting overall survival in Chinese triple-negative breast cancer patients after surgery
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Wei-Xun Lin, Yan-Na Xie, Yao-Kun Chen, Jie-Hui Cai, Juan Zou, Jie-Hua Zheng, Yi-Yuan Liu, Zhi-Yang Li and Ye-Xi Chen |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Special Fund Project of Guangdong Science and Technology |
210728156901524, 210728156901519, 210714096870447 |
| Medical Scientific Research Foundation of Guangdong Province |
A2021432, B2021448 |
| Shantou Medical Science and Technology Planning Project |
200622115260639, 210521236491457, 210625106490696 |
| Undergraduate Innovation Training Project of Shantou University |
31/38/47/54 |
|
| Corresponding Author |
Ye-Xi Chen, MD, Doctor, Doctor, Department of Thyroid, Breast and Hernia Surgery, The Second Affiliated Hospital of Shantou University Medical College, No. 69 North Dongxia Road, Shantou 515041, Guangdong Province, China. yxchen3@stu.edu.cn |
| Key Words |
Triple-negative breast cancer; Chinese; nomogram; Risk stratification; Overall survival |
| Core Tip |
This study aimed to construct and validate a nomogram for overall survival (OS) of triple-negative breast cancer (TNBC) patients after surgery. The data from SEER*stat 8.3.5 of selected Chinese surgical patients with TNBC between 2010 and 2015 were used. The multivariable analysis showed that age (P = 0.043), marital status (P = 0.040), tumor localization (P = 0.030), grade (P = 0.035), T classification (P = 0.012), and N classification (P = 0.002) were independent prognostic factors. A risk stratification model was generated. The C-indexes of the nomogram to predict OS were 0.766 and and compared to the seventh edition tumor, node and metastasis (TNM) staging system, which was higher (0.766 vs 0.707, P < 0.001). The nomogram provided a clear prognostic superiority over the traditional TNM system. |
| Publish Date |
2022-10-27 04:55 |
| Citation |
Lin WX, Xie YN, Chen YK, Cai JH, Zou J, Zheng JH, Liu YY, Li ZY, Chen YX. Nomogram for predicting overall survival in Chinese triple-negative breast cancer patients after surgery. World J Clin Cases 2022; 10(31): 11338-11348 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i31/11338.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i31.11338 |
