Publication Name	World Journal of Gastroenterology
Manuscript ID	71559
Country	United States

Received	2021-09-12 18:56
Peer-Review Started	2021-09-12 18:59
To Make the First Decision
Return for Revision	2021-10-16 03:26
Revised	2021-10-18 21:46
Second Decision	2021-12-29 03:10
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2021-12-31 21:56
Articles in Press	2021-12-31 21:56
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-01-05 07:28
Publish the Manuscript Online	2022-01-11 08:34

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Case Control Study
Article Title	Obesity is associated with decreased risk of microscopic colitis in women
Manuscript Source	Unsolicited Manuscript
All Author List	Robert S Sandler, Temitope O Keku, John T Woosley, Dale P Sandler, Joseph A Galanko and Anne F Peery
ORCID	Author(s) ORCID Number Robert S Sandler http://orcid.org/0000-0002-1323-6245 Temitope O Keku http://orcid.org/0000-0003-4019-3903 John T Woosley http://orcid.org/0000-0001-5876-3068 Dale P Sandler http://orcid.org/0000-0002-6776-0018 Joseph A Galanko http://orcid.org/0000-0003-2304-4375 Anne F Peery http://orcid.org/0000-0002-2005-0780
Funding Agency and Grant Number	Funding Agency Grant Number National Institutes of Health P30 DK034987 National Institutes of Health R01 DK105114
Corresponding Author	Robert S Sandler, MD, Professor, Department of Medicine, University of North Carolina, 130 Mason Farm Road, Chapel Hill, NC 27514-7555, United States. rsandler@med.unc.edu
Key Words	Colitis; Microscopic/epidemiology; Humans; Diarrhea/epidemiology; Obesity
Core Tip	We conducted a case control study among patients undergoing colonoscopy for diarrhea. The analysis included 110 patients with microscopic colitis and 252 controls. Obesity was associated with a substantially lower risk of microscopic colitis among women that was not explained by weight loss following the onset of diarrhea. Ever use of birth control pills was associated with lower risk of microscopic colitis after adjusting for age, education and BMI. The mechanism could involve hormonal effects of obesity or the gut microbiome.
Publish Date	2022-01-11 08:34
Citation	Sandler RS, Keku TO, Woosley JT, Sandler DP, Galanko JA, Peery AF. Obesity is associated with decreased risk of microscopic colitis in women. World J Gastroenterol 2022; 28(2): 230-241
URL	https://www.wjgnet.com/1007-9327/full/v28/i2/230.htm
DOI	https://dx.doi.org/10.3748/wjg.v28.i2.230

Full Article (PDF)	WJG-28-230.pdf
Full Article (Word)	WJG-28-230.docx
Manuscript File	71559_Auto_Edited.docx
Answering Reviewers	71559-Answering reviewers.pdf
Audio Core Tip	71559-Audio core tip.m4a
Biostatistics Review Certificate	71559-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	71559-Conflict-of-interest statement.pdf
Copyright License Agreement	71559-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	71559-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s)	71559-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	71559-Institutional review board statement.pdf
Peer-review Report	71559-Peer-review(s).pdf
Scientific Misconduct Check	71559-Bing-Wang LL-2.png
Scientific Editor Work List	71559-Scientific editor work list.pdf
CrossCheck Report	71559-CrossCheck report.pdf