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Articles Published Processes
6/2/2022 12:11:47 PM | Browse: 580 | Download: 1596
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Received |
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2021-09-13 22:21 |
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Peer-Review Started |
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2021-09-13 22:23 |
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To Make the First Decision |
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Return for Revision |
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2021-11-16 20:00 |
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Revised |
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2021-12-08 07:18 |
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Second Decision |
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2022-04-26 02:19 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-04-26 20:55 |
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Articles in Press |
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2022-04-26 20:55 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-04-14 22:41 |
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Typeset the Manuscript |
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2022-05-20 08:21 |
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Publish the Manuscript Online |
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2022-06-02 12:11 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Viral hepatitis and hepatocellular carcinoma: From molecular pathways to the role of clinical surveillance and antiviral treatment
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Leonardo Stella, Francesco Santopaolo, Antonio Gasbarrini, Maurizio Pompili and Francesca Romana Ponziani |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Francesca Romana Ponziani, MD, PhD, Research Assistant, Internal Medicine and Gastroenterology, Hepatology Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Largo Agostino Gemelli 8, Rome 00168, Italy. francesca.ponziani@gmail.com |
| Key Words |
Hepatitis C virus; Hepatitis B virus; Hepatitis D virus; Hepatocellular carcinoma; Cirrhosis; Liver |
| Core Tip |
Chronic hepatitis B virus (HBV), hepatitis C virus (HCV) and hepatitis D virus (HDV) infection represents a global health burden leading to liver fibrosis, cirrhosis and hepatocellular carcinoma (HCC). Among these complications, HCC accounts for 3.5% of all deaths worldwide. Thus, the understanding of the role of chronic hepatitis virus infection in HCC development is necessary in order to clarify the mechanisms underlying oncogenesis and design future treatments for this cancer. This review outlines pathophysiological and molecular pathways that contribute to carcinogenesis in HBV, HCV and HDV chronic infection focusing on the impact of clinical surveillance and antiviral treatment on the risk of HCC development. |
| Publish Date |
2022-06-02 12:11 |
| Citation |
Stella L, Santopaolo F, Gasbarrini A, Pompili M, Ponziani FR. Viral hepatitis and hepatocellular carcinoma: From molecular pathways to the role of clinical surveillance and antiviral treatment. World J Gastroenterol 2022; 28(21): 2251-2281 |
| URL |
https://www.wjgnet.com/1007-9327/full/v28/i21/2251.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v28.i21.2251 |
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