Publication Name	World Journal of Biological Chemistry
Manuscript ID	7174
Country	Sweden

Received	2013-11-07 11:41
Peer-Review Started	2013-11-07 17:39
To Make the First Decision	2013-12-02 11:48
Return for Revision	2013-12-10 20:37
Revised	2013-12-17 19:53
Second Decision	2014-01-14 18:55
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-01-14 20:03
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-02-07 19:16
Typeset the Manuscript	2014-02-26 11:19
Publish the Manuscript Online	2014-03-19 21:35

ISSN	1949-8454 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Biochemistry & Molecular Biology
Manuscript Type	Minireviews
Article Title	Thioredoxin and glutaredoxin-mediated redox regulation of ribonucleotide reductase
Manuscript Source	Invited Manuscript
All Author List	Rajib Sengupta and Arne Holmgren
Funding Agency and Grant Number	Funding Agency Grant Number Swedish Research Council Medicine 3529 Swedish Cancer Society 961 Wallenberg Foundation
Corresponding Author	Rajib Sengupta, PhD, Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Scheeles Vag 2, SE-17177 Stockholm, Sweden. rajib.sengupta@ki.se
Key Words	Ribonucleotide reductase; Thioredoxin; Glutaredoxin; DNA synthesis; Thiol disulfides; Replication
Core Tip	Thioredoxin and glutaredoxin-mediated redox regulations of ribonucleotide reductase (RNR) catalysis plays a vital role as the RNR catalysis involves different redox active thiol functions, thiyl radicals and thiol proteins. The in depth knowledge of the whole redox catalysis will contribute significantly to designing and developing new RNR inhibitors for improved cancer chemotherapy, antibiotic development and antiviral treatments.
Publish Date	2014-03-19 21:35
Citation	Sengupta R, Holmgren A. Thioredoxin and glutaredoxin-mediated redox regulation of ribonucleotide reductase. World J Biol Chem 2014; 5(1): 68-74 Available from: URL: http://www.wjgnet.com/1949-8454/full/v5/i1/68.htm DOI: http://dx.doi.org/10.4331/wjbc.v5.i1.68
URL	http://www.wjgnet.com/1949-8454/full/v5/i1/68.htm
DOI	http://dx.doi.org/10.5497/wjp.v2.i4.92

Manuscript File	7174-Review.doc
Answering Reviewers	7174-Answering reviewers.pdf
Copyright License Agreement	7174-Copyright assignment.pdf
Peer-review Report	7174-Peer reviewer(s).pdf
Scientific Editor Work List	7174-Scientific editor work list.doc