Publication Name	World Journal of Gastroenterology
Manuscript ID	7198
Country	Spain

Received	2013-11-11 09:17
Peer-Review Started	2013-11-13 11:19
To Make the First Decision	2013-12-16 18:10
Return for Revision	2013-12-20 17:46
Revised	2014-01-15 23:27
Second Decision	2014-03-19 13:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-03-19 15:22
Articles in Press	2014-05-23 11:18
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-04-14 23:36
Typeset the Manuscript	2014-06-20 13:31
Publish the Manuscript Online	2014-07-14 17:39

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Randomized Clinical Trial
Article Title	I.31, a new combination of probiotics, improves irritable bowel syndrome-related quality of life
Manuscript Source	Invited Manuscript
All Author List	Vicente Lorenzo-Zúñiga, Elba Llop, Cristina Suárez, Beatriz Álvarez, Luis Abreu, Jordi Espadaler and Jordi Serra
Funding Agency and Grant Number	Funding Agency Grant Number Spanish Ministry of Health, Instituto de Salud Carlos III (in part) PI10/02135
Corresponding Author	Jordi Serra, MD, PhD, Gastroenterology, Motility and Functional Gut Disorders Unit, Hospital Universitari Germans Trias i Pujol/CIBERehd, Carretera del Canyet s/n, 08916 Badalona, Spain. jserrap.germanstrias@gencat.cat
Key Words	Irritable bowel syndrome; Probiotic combination; Irritable bowel syndrome; Quality-of-life
Core Tip	Irritable bowel syndrome (IBS) is a benign functional gut disorder, and its severity is closely related to the impact of the disorder on quality of life. Probiotic bacteria have been shown to have a modest beneficial effect on abdominal symptoms in patients with IBS, but the effect of probiotics on IBS-related quality of life (IBS-QoL) is unclear. The present study was designed to specifically address the effect of a probiotic combination (I.31) on IBS-QoL, and demonstrates that I.31 is superior to placebo in improving IBS-QoL. These data suggest that I.31 may be beneficial for the global management of this complex disorder.
Publish Date	2014-07-14 17:39
Citation	Lorenzo-Zúñiga V, Llop E, Suárez C, Álvarez B, Abreu L, Espadaler J, Serra J. I.31, a new combination of probiotics, improves irritable bowel syndrome-related quality of life. World J Gastroenterol 2014; 20(26): 8709-8716
URL	http://www.wjgnet.com/1007-9327/full/v20/i26/8709.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i26.8709

Full Article (PDF)	WJG-20-8709.pdf
Full Article (Word)	WJG-20-8709.doc
Manuscript File	7198-Review.doc
Answering Reviewers	7198-Answering reviewers.pdf
Copyright License Agreement	7198-Copyright assignment.pdf
Peer-review Report	7198-Peer reviewer(s).pdf
Scientific Editor Work List	7198-Scientific editor work list.doc