Publication Name	World Journal of Diabetes
Manuscript ID	71980
Country	China

Received	2021-10-02 03:24
Peer-Review Started	2021-10-02 03:54
First Decision by Editorial Office Director	2022-01-12 05:42
Return for Revision	2022-01-15 12:14
Revised	2022-01-18 12:33
Publication Fee Transferred
Second Decision by Editor	2022-03-11 06:06
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2022-03-17 04:58
Articles in Press	2022-03-17 04:58
Edit the Manuscript by Language Editor	2022-03-09 11:32
Typeset the Manuscript	2022-04-07 06:28
Publish the Manuscript Online	2022-04-14 11:27

ISSN	1948-9358 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Biochemistry & Molecular Biology
Manuscript Type	Basic Study
Article Title	Roles of transient receptor potential channel 6 in glucose-induced cardiomyocyte injury
Manuscript Source	Unsolicited Manuscript
All Author List	Shi-Jun Jiang
ORCID	Author(s) ORCID Number Shi-Jun Jiang http://orcid.org/0000-0002-0688-5132
Funding Agency and Grant Number
Corresponding Author	Shi-Jun Jiang, MM, Research Fellow, School of Basic Medicine, Huazhong University of Science and Technology, No. 13 Aviation Road, Qiaokou District, Wuhan 430030, Hubei Province, China. jiangsj_89756@163.com
Key Words	Diabetic cardiomyopathy; Apoptosis; Proliferation; H9C2 cells; Transient receptor potential channel 6; P-calmodulin dependent protein kinase II
Core Tip	Diabetic cardiomyopathy is a serious complication of end-stage diabetes that presents symptoms such as cardiac hypertrophy and heart failure. The transient receptor potential channel 6 (TRPC6) protein is a very important selective calcium channel that is closely related to the development of various cardiomyopathies. We found that the inhibition of apoptosis and proliferation of cardiomyocytes in a high-glucose environment might be closely related to the activation of the TRPC6/P-calmodulin-dependent protein kinase II pathway.
Publish Date	2022-04-14 11:27
Citation	Jiang SJ. Roles of transient receptor potential channel 6 in glucose-induced cardiomyocyte injury. World J Diabetes 2022; 13(4): 338-357
URL	https://www.wjgnet.com/1948-9358/full/v13/i4/338.htm
DOI	https://dx.doi.org/10.4239/wjd.v13.i4.338

Full Article (PDF)	WJD-13-338.pdf
Full Article (Word)	WJD-13-338.docx
Manuscript File	71980_Auto_Edited-JRF-Wang TQ.docx
Answering Reviewers	71980-Answering reviewers.pdf
Audio Core Tip	71980-Audio core tip.m4a
Biostatistics Review Certificate	71980-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	71980-Conflict-of-interest statement.pdf
Copyright License Agreement	71980-Copyright license agreement.pdf
Institutional Animal Care and Use Committee Approval Form or Document	71980-Institutional animal care and use committee statement.pdf
Non-Native Speakers of English Editing Certificate	71980-Language certificate.pdf
Supplementary Material	71980-Supplementary material.pdf
Peer-review Report	71980-Peer-review(s).pdf
Scientific Misconduct Check	71980-Bing-Fan JR-2.png
Scientific Editor Work List	71980-Scientific editor work list.pdf
CrossCheck Report	71980-CrossCheck report.pdf
CrossCheck Report	71980-CrossCheck.png