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4/21/2022 11:35:30 AM | Browse: 284 | Download: 509
Publication Name World Journal of Clinical Cases
Manuscript ID 72031
Country China
Received
2021-10-01 13:35
Peer-Review Started
2021-10-01 13:37
To Make the First Decision
Return for Revision
2021-12-10 02:00
Revised
2021-12-24 12:21
Second Decision
2022-02-28 05:42
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-03-06 21:51
Articles in Press
2022-03-06 21:51
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-04-02 00:36
Publish the Manuscript Online
2022-04-21 11:35
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Surgery
Manuscript Type Observational Study
Article Title Surgery in platinum-resistant recurrent epithelial ovarian carcinoma
Manuscript Source Unsolicited Manuscript
All Author List Ling-Qin Zhao, Wen Gao, Ping Zhang, Ying-Li Zhang, Chen-Yan Fang and Hua-Feng Shou
ORCID
Author(s) ORCID Number
Ling-Qin Zhao http://orcid.org/0000-0001-7029-2887
Wen Gao http://orcid.org/0000-0002-8518-5299
Ping Zhang http://orcid.org/0000-0002-1707-2866
Ying-Li Zhang http://orcid.org/0000-0003-2002-6083
Chen-Yan Fang http://orcid.org/0000-0001-5383-1797
Hua-Feng Shou http://orcid.org/0000-0002-4664-2733
Funding Agency and Grant Number
Funding Agency Grant Number
Medical Science Project of Zhejiang Province 2018KY027
Corresponding Author Hua-Feng Shou, MD, N/A, Department of Gynecology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, No.158 Shangtang Road, Xiacheng District,Hangzhou, Zhejiang, Zhejiang 310014, China. shouhuafeng@hmc.edu.cn
Key Words Carcinoma; Ovarian epithelial; Cisplatin; Drug resistance; Neoplasm; Surgical treatment
Core Tip This retrospective study examined 38 patients with platinum-resistant epithelial ovarian carcinoma (EOC). R0 resection was achieved in 25 (65.8%) and R1/2 in 13 (34.2%). Twenty-five (65.8%) patients required organ resection. Nine (23.7%) patients had operative complications, 36 (94.7%) received chemotherapy, and five (13.2%) had targeted therapy. Median progression-free survival (PFS) and overall survival (OS) were 10 and 28 mo, respectively; median chemotherapy-free interval (CFI) was 9 mo. R0 resection and postoperative chemotherapy significantly prolonged PFS and OS, and R0 resection also significantly prolonged CFI. Overall, these findings indicated secondary cytoreductive surgery is feasible for the treatment of platinum-resistant recurrent EOC.
Publish Date 2022-04-21 11:35
Citation Zhao LQ, Gao W, Zhang P, Zhang YL, Fang CY, Shou HF. Surgery in platinum-resistant recurrent epithelial ovarian carcinoma. World J Clin Cases 2022; 10(12): 3739-3753
URL https://www.wjgnet.com/2307-8960/full/v10/i12/3739.htm
DOI https://dx.doi.org/10.12998/wjcc.v10.i12.3739
Full Article (PDF) WJCC-10-3739.pdf
Full Article (Word) WJCC-10-3739.docx
Manuscript File 72031_Auto_Edited-LJH.docx
Answering Reviewers 72031-Answering reviewers.pdf
Audio Core Tip 72031-Audio core tip.mp3
Biostatistics Review Certificate 72031-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 72031-Conflict-of-interest statement.pdf
Copyright License Agreement 72031-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 72031-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 72031-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 72031-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 72031-Language certificate.pdf
Peer-review Report 72031-Peer-review(s).pdf
Scientific Misconduct Check 72031-Bing-Liu JH-2.jpg
Scientific Misconduct Check 72031-CrossCheck.jpg
Scientific Editor Work List 72031-Scientific editor work list.pdf