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Articles Published Processes
4/21/2022 11:35:30 AM | Browse: 423 | Download: 895
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Received |
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2021-10-01 13:35 |
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Peer-Review Started |
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2021-10-01 13:37 |
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To Make the First Decision |
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Return for Revision |
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2021-12-10 02:00 |
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Revised |
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2021-12-24 12:21 |
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Second Decision |
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2022-02-28 05:42 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-03-06 21:51 |
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Articles in Press |
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2022-03-06 21:51 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-04-02 00:36 |
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Publish the Manuscript Online |
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2022-04-21 11:35 |
ISSN |
2307-8960 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Surgery |
Manuscript Type |
Observational Study |
Article Title |
Surgery in platinum-resistant recurrent epithelial ovarian carcinoma
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Ling-Qin Zhao, Wen Gao, Ping Zhang, Ying-Li Zhang, Chen-Yan Fang and Hua-Feng Shou |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Medical Science Project of Zhejiang Province |
2018KY027 |
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Corresponding Author |
Hua-Feng Shou, MD, N/A, N/A, Department of Gynecology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, No.158 Shangtang Road, Xiacheng District,Hangzhou, Zhejiang, Zhejiang 310014, China. shouhuafeng@hmc.edu.cn |
Key Words |
Carcinoma; Ovarian epithelial; Cisplatin; Drug resistance; Neoplasm; Surgical treatment |
Core Tip |
This retrospective study examined 38 patients with platinum-resistant epithelial ovarian carcinoma (EOC). R0 resection was achieved in 25 (65.8%) and R1/2 in 13 (34.2%). Twenty-five (65.8%) patients required organ resection. Nine (23.7%) patients had operative complications, 36 (94.7%) received chemotherapy, and five (13.2%) had targeted therapy. Median progression-free survival (PFS) and overall survival (OS) were 10 and 28 mo, respectively; median chemotherapy-free interval (CFI) was 9 mo. R0 resection and postoperative chemotherapy significantly prolonged PFS and OS, and R0 resection also significantly prolonged CFI. Overall, these findings indicated secondary cytoreductive surgery is feasible for the treatment of platinum-resistant recurrent EOC. |
Publish Date |
2022-04-21 11:35 |
Citation |
Zhao LQ, Gao W, Zhang P, Zhang YL, Fang CY, Shou HF. Surgery in platinum-resistant recurrent epithelial ovarian carcinoma. World J Clin Cases 2022; 10(12): 3739-3753 |
URL |
https://www.wjgnet.com/2307-8960/full/v10/i12/3739.htm |
DOI |
https://dx.doi.org/10.12998/wjcc.v10.i12.3739 |
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