Publication Name	World Journal of Clinical Cases
Manuscript ID	72120
Country	China

Received	2021-10-31 02:39
Peer-Review Started	2021-10-31 02:40
To Make the First Decision
Return for Revision	2021-12-27 07:07
Revised	2022-01-10 16:47
Second Decision	2022-05-10 02:54
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-05-14 07:26
Articles in Press	2022-05-14 07:26
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-04-24 01:22
Typeset the Manuscript	2022-06-25 14:40
Publish the Manuscript Online	2022-07-05 01:22

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Pediatrics
Manuscript Type	Case Report
Article Title	A 7-year-old boy with recurrent cyanosis and tachypnea: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Shu Li, Li-Na Chen and Lin Zhong
ORCID	Author(s) ORCID Number Shu Li http://orcid.org/0000-0001-9126-1131 Li-Na Chen http://orcid.org/0000-0001-9537-8847 Lin Zhong http://orcid.org/0000-0003-0587-3460
Funding Agency and Grant Number	Funding Agency Grant Number The science&Technology department of Sichuan Province 2020YFS0105 The West China Second University Hospital of Sichuan University KL036
Corresponding Author	Lin Zhong, MD, Attending Doctor, Department of Pediatric Pulmonology and Immunology, West China Second University Hospital of Sichuan University, No. 1416, Chenglong Road, Chengdu 610066, Sichuan Province, China. linca_zhong@163.com
Key Words	Respiratory failure; Pulmonary heart disease; Sleep-related breathing disorders; Pleomorphic xanthoastrocytoma; Children; Case report
Core Tip	Brain tumors are the most common solid tumors in children. Common presentations include headache, nausea and vomiting, gait abnormality, and epileptic seizure; however, some symptoms can be insidious and misleading. Here, we report a 7-year-old boy who presented with recurrent cyanosis and tachypnea after exercise for 2 years. Type II respiratory failure, pulmonary heart disease, liver injury, and severe obesity were diagnosed. Cyanosis during sleep (peripheral oxygen saturation dropping to 50%-60%) was observed during hospitalization. Sleep-related breathing disorder was suspected. Brain magnetic resonance imaging revealed a cerebellum and brainstem space-occupying lesion. Subsequent tissue biopsy pathology confirmed brainstem pleomorphic xanthoastrocytoma.
Publish Date	2022-07-05 01:22
Citation	Li S, Chen LN, Zhong L. A 7-year-old boy with recurrent cyanosis and tachypnea: A case report. World J Clin Cases 2022; 10(20): 6974-6980
URL	https://www.wjgnet.com/2307-8960/full/v10/i20/6974.htm
DOI	https://dx.doi.org/10.12998/wjcc.v10.i20.6974

Full Article (PDF)	WJCC-10-6974.pdf
Full Article (Word)	WJCC-10-6974.docx
CARE Checklist–2016	72120-CARE-Checklist–2016-revision.jpeg
Manuscript File	72120_Auto_Edited-XRG-Filipodia-LS.docx
Answering Reviewers	72120-Answering reviewers.pdf
Audio Core Tip	72120-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	72120-Conflict-of-interest statement.pdf
Copyright License Agreement	72120-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	72120-Grant application form(s).pdf
Signed Consent for Treatment Form(s) or Document(s)	72120-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	72120-Language certificate.pdf
Peer-review Report	72120-Peer-review(s).pdf
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Scientific Editor Work List	72120-Scientific editor work list.pdf
CrossCheck Report	72120-CrossCheck report.pdf