Publication Name	World Journal of Gastroenterology
Manuscript ID	72135
Country	United States

Received	2021-10-28 21:59
Peer-Review Started	2021-10-28 22:01
To Make the First Decision
Return for Revision	2021-12-26 22:01
Revised	2022-01-27 01:23
Second Decision	2022-05-26 02:27
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-05-28 03:32
Articles in Press	2022-05-28 03:32
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-06-22 03:29
Publish the Manuscript Online	2022-07-04 12:30

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Immunology
Manuscript Type	Review
Article Title	Inflammation, microbiome and colorectal cancer disparity in African-Americans: Are there bugs in the genetics?
Manuscript Source	Unsolicited Manuscript
All Author List	Sami Ahmad, Hassan Ashktorab, Hassan Brim and Franck Housseau
ORCID	Author(s) ORCID Number Sami Ahmad http://orcid.org/0000-0001-5838-3137 Hassan Ashktorab http://orcid.org/0000-0002-4048-4666 Hassan Brim http://orcid.org/0000-0001-7055-2298 Franck Housseau http://orcid.org/0000-0002-7028-3953
Funding Agency and Grant Number
Corresponding Author	Franck Housseau, PharmD, PhD, Associate Professor, Department of Oncology, Johns Hopkins University, CRB1 4M59 1650 Orleans street, Baltimore, MD 21231, United States. fhousse1@jhmi.edu
Key Words	Inflammation; African-American; Population-specific genome wide association studies; Minorities health; Microbiome; Colorectal cancer
Core Tip	Studies largely examine either variations in microbiome composition or host immunity polymorphisms, often using genome-wide association studies comprised of populations mainly of European ancestry. There is, thus, a pressing need for studies that include, recruit, and account for more widely diverse cohorts. Identification of population-associated polymorphisms driving host/microbiome interactions linked to colorectal cancer (CRC) disparity may reveal genes or pathways that could be targeted for patient-specific CRC interception strategies.
Publish Date	2022-07-04 12:30
Citation	Ahmad S, Ashktorab H, Brim H, Housseau F. Inflammation, microbiome and colorectal cancer disparity in African-Americans: Are there bugs in the genetics? World J Gastroenterol 2022; 28(25): 2782-2801
URL	https://www.wjgnet.com/1007-9327/full/v28/i25/2782.htm
DOI	https://dx.doi.org/10.3748/wjg.v28.i25.2782

Full Article (PDF)	WJG-28-2782.pdf
Full Article (Word)	WJG-28-2782.docx
Manuscript File	72135_Auto_Edited-LS.docx
Answering Reviewers	72135-Answering reviewers.pdf
Audio Core Tip	72135-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	72135-Conflict-of-interest statement.pdf
Copyright License Agreement	72135-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	72135-Language certificate.pdf
Peer-review Report	72135-Peer-review(s).pdf
Scientific Misconduct Check	72135-Bing-Wang JJ-2.png
Scientific Editor Work List	72135-Scientific editor work list.pdf
CrossCheck Report	72135-CrossCheck report.pdf